Subscribe to RSS
DOI: 10.1055/a-2025-3529
Transbulbäre und transgastrale Gallengangsdrainage
Indikation, Durchführung, KomplikationenDie endoskopisch retrograde Cholangiopankreatikografie (ERCP) ist der Goldstandard für die Drainage der obstruktiven Cholestase maligner und benigner Erkrankungen, mit einer geringen Misserfolgsrate von 4–16% [1]. Bei fehlgeschlagener ERCP stehen verschiedene endosonografisch geführte Rescue-Verfahren (EUS-BD) zur Verfügung, deren Indikation und Durchführung im Folgenden vorgestellt werden.
-
EUS-geführte biliäre Drainagen (EUS-BD) stellen eine Gruppe von „Rescue-Verfahren“ nach fehlgeschlagener ERCP dar.
-
Sie ermöglichen einen direkten Zugang zu den Gallengängen vom Magen oder vom Duodenum aus, ohne dass die Papille zwingend erreicht werden muss.
-
Transduodenal lassen sich der extrahepatische Ductus (hepato-)choledochus und transgastral intrahepatische Gallengänge im linken Leberlappen punktieren.
-
Die Drainagenplatzierung am Zielort erfolgt entweder in Seldinger-Technik (prinzipiell für alle Verfahren realisierbar) oder als Direktpunktionsverfahren bei der EUS-gesteuerten Choledochoduodenostomie und Gallenblasendrainage.
-
Die optimale Drainagestrategie richtet sich nach dem Ort der Obstruktion (distal/hilär) und der zugrunde liegenden Erkrankung (benigne/maligne).
-
Es handelt sich um komplexe Verfahren, bei denen das Ergebnis maßgeblich durch die Fähigkeiten und Erfahrung des Untersuchers und der Expertise des Teams des gesamten Zentrums determiniert wird.
-
Technische und klinische Erfolgsraten von 90% und darüber sind nach Datenlage erreichbar und stellen die Zielvorgabe dar.
-
Je nach Verfahren ist mit Komplikationen in ca. 5–18% der Fälle zu rechnen. Diese sind in der Regel konservativ oder endoskopisch beherrschbar.
Schlüsselwörter
endoskopisch retrograd - Cholangiopankreatikografie - endoskopischer Ultraschall - biliäre Drainage - EUS-geführtPublication History
Article published online:
20 March 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Holt BA, Hawes R, Hasan M. et al. Biliary drainage: role of EUS guidance. Gastrointest Endosc 2016; 83: 160-165
- 2 Glazer ES, Hornbrook MC, Krouse RS. A meta-analysis of randomized trials: immediate stent placement vs. surgical bypass in the palliative management of malignant biliary obstruction. J Pain Symptom Manage 2014; 47: 307-314
- 3 Godat S, Bories E, Caillol F. et al. Efficacy and safety in case of technical success of endoscopic ultrasound-guided transhepatic antegrade biliary drainage: A report of a monocentric study. Endosc Ultrasound 2017; 6: 181-186
- 4 Khashab MA, Valeshabad AK, Afghani E. et al. A comparative evaluation of EUS-guided biliary drainage and percutaneous drainage in patients with distal malignant biliary obstruction and failed ERCP. Dig Dis Sci 2015; 60: 557-565
- 5 Nam K, Kim DU, Lee TH. et al. Patient perception and preference of EUS-guided drainage over percutaneous drainage when endoscopic transpapillary biliary drainage fails: An international multicenter survey. Endosc Ultrasound 2018; 7: 48-55
- 6 Sharaiha RZ, Khan MA, Kamal F. et al. Efficacy and safety of EUS-guided biliary drainage in comparison with percutaneous biliary drainage when ERCP fails: a systematic review and meta-analysis. Gastrointest Endosc 2017; 85: 904-914
- 7 van der Merwe SW, van Wanrooij RLJ, Bronswijk M. et al. Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2022; 54: 185-205
- 8 Veitch AM, Radaelli F, Alikhan R. et al. Endoscopy in patients on antiplatelet or anticoagulant therapy: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guideline update. Endoscopy 2021; 53: 947-969
- 9 Lange CM, Fichtlscherer S, Miesbach W. et al. The Periprocedural Management of Anticoagulation and Platelet Aggregation Inhibitors in Endoscopic Interventions. Dtsch Arztebl Int 2016; 113: 129-135
- 10 Chantarojanasiri T, Ratanachu-Ek T, Pausawasdi N. What You Need to Know Before Performing Endoscopic Ultrasound-guided Hepaticogastrostomy. Clin Endosc 2021; 54: 301-308
- 11 Kamata K, Takenaka M, Minaga K. et al. Stent migration during EUS-guided hepaticogastrostomy in a patient with massive ascites: Troubleshooting using additional EUS-guided antegrade stenting. Arab J Gastroenterol 2017; 18: 120-121
- 12 Denzer U, Beilenhoff U, Eickhoff A. et al. [S2k guideline: quality requirements for gastrointestinal endoscopy, AWMF registry no. 021–022]. Z Gastroenterol 2015; 53: 1496-1530
- 13 Johnson G, Webster G, Boškoski I. et al. Curriculum for ERCP and endoscopic ultrasound training in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy 2021; 53: 1071-1087
- 14 Jovani M, Ichkhanian Y, Parsa N. et al. Assessment of the learning curve for EUS-guided gastroenterostomy for a single operator. Gastrointest Endosc 2021; 93: 1088-1093
- 15 Oh D, Park DH, Song TJ. et al. Optimal biliary access point and learning curve for endoscopic ultrasound-guided hepaticogastrostomy with transmural stenting. Therap Adv Gastroenterol 2017; 10: 42-53
- 16 Tyberg A, Mishra A, Cheung M. et al. Learning curve for EUS-guided biliary drainage: What have we learned?. Endosc Ultrasound 2020; 9: 392-396
- 17 Krishnamoorthi R, Dasari CS, Thoguluva Chandrasekar V. et al. Effectiveness and safety of EUS-guided choledochoduodenostomy using lumen-apposing metal stents (LAMS): a systematic review and meta-analysis. Surg Endosc 2020; 34: 2866-2877
- 18 Lu L, Tang X, Jin H. et al. Endoscopic Ultrasound-Guided Biliary Drainage Using Self-Expandable Metal Stent for Malignant Biliary Obstruction. Gastroenterol Res Pract 2017; 2017: 6284094
- 19 Minaga K, Ogura T, Shiomi H. et al. Comparison of the efficacy and safety of endoscopic ultrasound-guided choledochoduodenostomy and hepaticogastrostomy for malignant distal biliary obstruction: Multicenter, randomized, clinical trial. Dig Endosc 2019; 31: 575-582
- 20 Itoi T, Binmoeller K, Itokawa F. et al. Endoscopic ultrasonography-guided cholecystogastrostomy using a lumen-apposing metal stent as an alternative to extrahepatic bile duct drainage in pancreatic cancer with duodenal invasion. Dig Endosc 2013; 25 (Suppl. 2) 137-141
- 21 Will U, Thieme A, Fueldner F. et al. Treatment of biliary obstruction in selected patients by endoscopic ultrasonography (EUS)-guided transluminal biliary drainage. Endoscopy 2007; 39: 292-295
- 22 Kamal F, Khan MA, Lee-Smith W. et al. Efficacy and safety of EUS-guided gallbladder drainage for rescue treatment of malignant biliary obstruction: A systematic review and meta-analysis. Endosc Ultrasound 2023; 12: 8-15
- 23 Burmester E, Niehaus J, Leineweber T. et al. EUS-cholangio-drainage of the bile duct: report of 4 cases. Gastrointest Endosc 2003; 57: 246-251
- 24 van Wanrooij RLJ, Bronswijk M, Kunda R. et al. Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review. Endoscopy 2022; 54: 310-332
- 25 Anderloni A, Fugazza A, Troncone E. et al. Single-stage EUS-guided choledochoduodenostomy using a lumen-apposing metal stent for malignant distal biliary obstruction. Gastrointest Endosc 2019; 89: 69-76
- 26 Hedjoudje A, Sportes A, Grabar S. et al. Outcomes of endoscopic ultrasound-guided biliary drainage: A systematic review and meta-analysis. United European Gastroenterol J 2019; 7: 60-68
- 27 Dhindsa BS, Mashiana HS, Dhaliwal A. et al. EUS-guided biliary drainage: A systematic review and meta-analysis. Endosc Ultrasound 2020; 9: 101-109
- 28 Teoh AYB, Napoleon B, Kunda R. et al. EUS-Guided Choledocho-duodenostomy Using Lumen Apposing Stent Versus ERCP With Covered Metallic Stents in Patients With Unresectable Malignant Distal Biliary Obstruction: A Multicenter Randomized Controlled Trial (DRA-MBO Trial). Gastroenterology 2023; 165: 473-482.e2
- 29 Chen YI, Sahai A, Donatelli G. et al. Endoscopic Ultrasound-Guided Biliary Drainage of First Intent With a Lumen-Apposing Metal Stent vs Endoscopic Retrograde Cholangiopancreatography in Malignant Distal Biliary Obstruction: A Multicenter Randomized Controlled Study (ELEMENT Trial). Gastroenterology 2023; 165: 1249-1261.e5
- 30 Imai H, Kitano M, Omoto S. et al. EUS-guided gallbladder drainage for rescue treatment of malignant distal biliary obstruction after unsuccessful ERCP. Gastrointest Endosc 2016; 84: 147-151
- 31 Chang JI, Dong E, Kwok KK. Endoscopic ultrasound-guided transmural gallbladder drainage in malignant obstruction using a novel lumen-apposing stent: a case series (with video). Endosc Int Open 2019; 7: E655-E661
- 32 Wang K, Zhu J, Xing L. et al. Assessment of efficacy and safety of EUS-guided biliary drainage: a systematic review. Gastrointest Endosc 2016; 83: 1218-1227
- 33 Khan MA, Akbar A, Baron TH. et al. Endoscopic Ultrasound-Guided Biliary Drainage: A Systematic Review and Meta-Analysis. Dig Dis Sci 2016; 61: 684-703
- 34 Paik WH, Lee TH, Park DH. et al. EUS-Guided Biliary Drainage Versus ERCP for the Primary Palliation of Malignant Biliary Obstruction: A Multicenter Randomized Clinical Trial. Am J Gastroenterol 2018; 113: 987-997
- 35 Kawakami H, Kuwatani M, Kawakubo K. et al. Candy-like sign during endoscopic ultrasound-guided choledochoduodenostomy as an indication of the long distance between the bile duct and duodenal wall. Endoscopy 2014; 46 (Suppl. 1) E406-E407
- 36 Garcia-Sumalla A, Loras C, Guarner-Argente C. et al. Is a coaxial plastic stent within a lumen-apposing metal stent useful for the management of distal malignant biliary obstruction?. Surg Endosc 2021; 35: 4873-4881
- 37 Attardo S, Auriemma F, Fugazza A. et al. Rescue management of recurrent duodenal and biliary obstruction due to lumen-apposing metal stent distal migration and duodenal stent ingrowth. Endoscopy 2019; 51: E118-E119