Vibrational Circular Dichroism Studies on Axially Chiral Carbodiimides and Allenes

Tohru Taniguchi

doi:10.1055/a-2071-4411

Synlett, Table of Contents

Synlett 2023; 34(16): 1839-1844
DOI: 10.1055/a-2071-4411

synpacts

Vibrational Circular Dichroism Studies on Axially Chiral Carbodiimides and Allenes

Tohru Taniguchi ∗

Abstract

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Abstract

The axial chirality of molecules with two consecutive double bonds (X=Y=Z) has not been well studied because of a lack of analytical methods and because of difficulties in their preparation in enantiomerically pure forms. This Synpacts article describes the use of vibrational circular dichroism spectroscopy to study the stereochemistry of carbodiimides and allenes. A strategy to obtain carbodiimides with one-handed chirality by using conformationally restrained frameworks is also discussed.

1 Introduction

2 Carbodiimides with Partially Biased Axial Chirality and One-Handed Axial Chirality

3 Axially Chiral Allenes

4 Conclusions

Key words

vibrational circular dichroism - carbodiimides - allenes - axial chirality - structural analysis

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References

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