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Synthesis 2023; 55(17): 2674-2682
DOI: 10.1055/a-2093-3233
DOI: 10.1055/a-2093-3233
paper
Acylation of Electron-Poor Alkenyl Sulfoxides: Diverse Transformations for the Synthesis of Polysubstituted Phenols and Functionalized Carbocycles
We gratefully acknowledge financial support from the National Natural Science Foundation of China (No. 22071082) and the Research and Application Service Platform Project of API Manufacturing Environmental Protection and Safety Technology in China (2020-0107-3-1).
Abstract
A protocol with available starting materials and mild conditions was developed for the synthesis of polysubstituted phenols and functionalized carbocycles via acylation of electron-poor alkenyl sulfoxides. The plausible mechanism was investigated.
Key words
alkenyl sulfoxides - sulfonium ions - functionalized carbocycles - polysubstituted phenols - aromatizationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2093-3233.
- Supporting Information
Publication History
Received: 23 February 2023
Accepted after revision: 15 May 2023
Accepted Manuscript online:
15 May 2023
Article published online:
12 June 2023
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