Synthesis, Table of Contents Synthesis 2024; 56(01): 171-178DOI: 10.1055/a-2175-1008 paper Synthesis of Oxindoles via SmI2-Promoted Reduction of 2-Nitrophenylacetic Acids Pengkai Wang , Songlin Zhang∗ Recommend Article Abstract Buy Article All articles of this category Abstract The reduction of 2-nitrophenylacetic acids to oxindoles promoted by SmI2 is reported for the first time. This reaction involving the reduction of nitro group proceeds through N–O bond cleavage and direct condensation with the neighboring carboxyl group. From a synthetic point of view, a new method for the synthesis of oxindoles in mild neutral conditions is developed. Key words Key wordssamarium diiodide - single electron transfer reagent - oxindoles Full Text References References 1a Goehring RR, Sachdeva YP, Pisipati JS, Sleevi MC, Wolfe JF. J. Am. Chem. Soc. 1985; 107: 435 1b Higuchi K, Kawasaki T. Nat. Prod. Rep. 2007; 24: 843 1c Naresh Babu K, Kariyandi NR, Saheeda MK. S, Kinthada LK, Bisai A. J. Org. 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