Transfusionen von Erythrozytenkonzentraten (EK) erfolgen bei akuten und/oder chronischen
Anämien zur Verhinderung bzw. Therapie einer anämischen Gewebehypoxie. Im Jahr 2022 wurden in
Deutschland rund 3,2 Mio. EK-Transfusionen durchgeführt [1]. Durch eine gezielte, leitliniengerechte
EK-Transfusion auf Grundlage physiologischer Transfusionstrigger können Organschäden durch eine
anämische Hypoxie vermieden werden.
Abstract
The aim of red blood cell (RBC) transfusion is to prevent or treat anemic tissue hypoxia
in acute or chronic anemia. In 2022, approximately 3.2 million red blood cell transfusions
were conducted in Germany. Most blood products are transfused in surgical medicine. RBC units
should be used appropriately, based on recent evidence about their indications, profound
knowledge on handling, correct documentation as well as possible associated risks of
transfusion-associated adverse events and their respective treatments. Blood loss in
particular increases the risk of an imbalance between oxygen supply and oxygen demand.
Targeted, rational (restrictive) blood transfusion based on physiological transfusion triggers
makes it possible to avoid organ injury due to anemic hypoxia.
Schlüsselwörter
Erythrozytenkonzentrat - Transfusion - Blutprodukt - Blutgruppe - Anämie
Keywords
red blood cells - transfusion - blood product - anemia
