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Zeitschrift für Phytotherapie 2024; 45(04): 157-162
DOI: 10.1055/a-2276-0265
Forschung

Pflanzliche Polyphenole sind Regulatoren der Verdauung mit therapeutischen Effekten

Plant polyphenols as regulators of digestion with therapeutic effects
Matthias F. Melzig
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Zusammenfassung

Polyphenole hemmen unspezifisch hydrolytische Enzyme, die am Verdauungsprozess beteiligt sind, z.B. Amylasen, Proteasen, Lipasen. Dadurch wird der Verdauungsprozess verzögert, was sich in einer unvollständigen Resorption von Monosacchariden, Fettsäuren und Aminosäuren sowie in einer erhöhten Menge von unverdauten Makronährstoffen im Ileum und Kolon äußert. Dadurch wird die postprandiale Blutkonzentration von Monosacchariden, Fettsäuren und Aminosäuren gesenkt und verschiedene Stoffwechselwege laufen langsamer ab. Eine polyphenolreiche Ernährung ist damit eine wirksame Strategie zur Verbesserung der Gesundheit von Patienten mit metabolischem Syndrom.

Abstract

Polyphenols non-specifically inhibit hydrolytic enzymes involved in the digestive process, e. g. amylases, proteases, lipases. Thus, the digestive process is delayed, resulting in incomplete absorption of monosaccharides, fatty acids and amino acids as well as increased amounts of undigested macronutrients in the ileum and colon. As a result, the postprandial blood concentration of monosaccharides, fatty acids and amino acids is reduced and various metabolic pathways run more slowly. A polyphenol-rich diet is therefore an effective strategy for improving the health of patients with metabolic syndrome.

Keywords

Polyphenols - hydrolases - enzyme inhibition - digestion - phytotherapy

Schlüsselwörter

Polyphenole - Hydrolasen - Enzymhemmung - Verdauung - Phytotherapie


Publication History

Article published online:
13 August 2024

© 2024. Thieme. All rights reserved.

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