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Anästhesiol Intensivmed Notfallmed Schmerzther 2025; 60(02): 71-73
DOI: 10.1055/a-2499-3183
Leserbrief

Leserbrief

Leserbrief zu Muskelrelaxierung bei pädiatrischen Patient*innen, Anästhesiol Intensivmed Notfallmed Schmerzther 2024; 59: 518 – 527, DOI: 10.1055/a-2348-2556
Christoph Unterbuchner
,
Katharina Ehehalt
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Letter to:

Muskelrelaxierung bei pädiatrischen Patient*innenAnästhesiol Intensivmed Notfallmed Schmerzther 2024; 59(09): 518-527
DOI: 10.1055/a-2348-2556

Sehr geehrte Herausgeber,

wir haben mit großem Interesse den CME-Fortbildungsartikel „Muskelrelaxierung bei pädiatrischen Patient*innen“ gelesen. Hierbei handelt es sich um ein essenzielles Thema im Bereich der Kinderanästhesie. Wir möchten hierzu einige Kommentare abgeben und Ergänzungen vornehmen, die uns als sehr wichtig erscheinen.



Publication History

Article published online:
17 February 2025

© 2025. Thieme. All rights reserved.

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Comment to this article:

Antwort zum Leserbrief zu „Muskelrelaxierung bei pädiatrischen Patient*innen“Anästhesiol Intensivmed Notfallmed Schmerzther 2025; 60(02): 74-74
DOI: 10.1055/a-2511-7314

 

  • Literatur

  • 1 Klucka J, Kosinova M, Krikava I. et al. Residual neuromuscular block in paediatric anaesthesia. Br J Anaesth 2019; 122: e1-e2
    CrossrefPubMedSearch in Google Scholar
  • 2 Ledowski T, OʼDea B, Meyerkort L. et al. Postoperative Residual Neuromuscular Paralysis at an Australian Tertiary Childrenʼs Hospital. Anesthesiol Res Pract 2015; 2015: 410248
    PubMedSearch in Google Scholar
  • 3 Faulk DJ, Austin TM, Thomas JJ. et al. A Survey of the Society for Pediatric Anesthesia on the Use, Monitoring, and Antagonism of Neuromuscular Blockade. Anesth Analg 2021; 132: 1518-1526
    PubMedSearch in Google Scholar
  • 4 Keil O, Rigterink V. [Neuromuscular Blockade in Paediatric Patients]. Anasthesiol Intensivmed Notfallmed Schmerzther 2024; 59: 518-527
    PubMedSearch in Google Scholar
  • 5 Keil O, Brunsmann K, Boethig D. et al. Incidence and characteristics of errors detected by a short team briefing in pediatric anesthesia. Paediatr Anaesth 2022; 32: 1144-1150
    CrossrefPubMedSearch in Google Scholar
  • 6 Scheffenbichler FT, Rudolph MI, Friedrich S. et al. Effects of high neuromuscular blocking agent dose on post-operative respiratory complications in infants and children. Acta Anaesthesiol Scand 2020; 64: 156-167
    CrossrefPubMedSearch in Google Scholar
  • 7 Soffer OD, Kim A, Underwood E. et al. Neurophysiological Assessment of Prolonged Recovery From Neuromuscular Blockade in the Neonatal Intensive Care Unit. Front Pediatr 2020; 8: 580
    CrossrefPubMedSearch in Google Scholar
  • 8 Guo J, Zhou X, Yuan X. et al. Age and the neuromuscular blockading effects of cisatracurium. Int J Clin Exp Med 2015; 8: 16664-16669
    PubMedSearch in Google Scholar
  • 9 von Ungern-Sternberg BS, Hammer J, Schibler A. et al. Decrease of functional residual capacity and ventilation homogeneity after neuromuscular blockade in anesthetized young infants and preschool children. Anesthesiology 2006; 105: 670-675
    CrossrefPubMedSearch in Google Scholar
  • 10 Trachsel D, Svendsen J, Erb TO. et al. Effects of anaesthesia on paediatric lung function. Br J Anaesth 2016; 117: 151-163
    CrossrefPubMedSearch in Google Scholar
  • 11 Isono S, Tanaka A, Ishikawa T. et al. Developmental changes in collapsibility of the passive pharynx during infancy. Am J Respir Crit Care Med 2000; 162: 832-836
    CrossrefPubMedSearch in Google Scholar
  • 12 Jalkanen L, Meretoja OA, Taivainen T. et al. Synergism between atracurium and mivacurium compared with that between vecuronium and mivacurium. Anesth Analg 1994; 79: 998-1002
    CrossrefPubMedSearch in Google Scholar
  • 13 Gilbertson LE, Fiedorek MC, Fiedorek CS. et al. Prolonged neuromuscular block after rocuronium administration in laparoscopic pyloromyotomy patients: A retrospective bayesian regression analysis. Paediatr Anaesth 2021; 31: 290-297
    CrossrefPubMedSearch in Google Scholar
  • 14 Vested M, Tarpgaard M, Eriksen K. et al. Incidence of residual neuromuscular blockade in children below 3 years after a single bolus of cisatracurium 0.1 mg/kg: A quality assurance study. Acta Anaesthesiol Scand 2020; 64: 168-172
    CrossrefPubMedSearch in Google Scholar
  • 15 Vanlinthout LE, Driessen JJ, Stolker RJ. et al. Spontaneous recovery from neuromuscular block after a single dose of a muscle relaxant in pediatric patients: A systematic review using a network meta-analytic and meta-regression approach. Paediatr Anaesth 2024; 34: 720-733
    CrossrefPubMedSearch in Google Scholar
  • 16 Fuchs-Buder T, Romero CS, Lewald H. et al. Peri-operative management of neuromuscular blockade: A guideline from the European Society of Anaesthesiology and Intensive Care. Eur J Anaesthesiol 2023; 40: 82-94
    CrossrefPubMedSearch in Google Scholar
  • 17 Nemes R, Fulesdi B, Pongracz A. et al. Impact of reversal strategies on the incidence of postoperative residual paralysis after rocuronium relaxation without neuromuscular monitoring: A partially randomised placebo controlled trial. Eur J Anaesthesiol 2017; 34: 609-616
    CrossrefPubMedSearch in Google Scholar
  • 18 Naguib M, Brull SJ, Kopman AF. et al. Consensus Statement on Perioperative Use of Neuromuscular Monitoring. Anesth Analg 2018; 127: 71-80
    CrossrefPubMedSearch in Google Scholar
  • 19 Rodney G, Raju P, Brull SJ. Neuromuscular block management: evidence-based principles and practice. BJA Educ 2024; 24: 13-22
    CrossrefPubMedSearch in Google Scholar
  • 20 von Ungern-Sternberg BS, Boda K, Chambers NA. et al. Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study. Lancet 2010; 376: 773-783
    CrossrefPubMedSearch in Google Scholar
  • 21 Meakin GH. Role of muscle relaxants in pediatric anesthesia. Curr Opin Anaesthesiol 2007; 20: 227-231
    CrossrefPubMedSearch in Google Scholar
  • 22 Meretoja OA. Neuromuscular block and current treatment strategies for its reversal in children. Paediatr Anaesth 2010; 20: 591-604
    CrossrefPubMedSearch in Google Scholar
  • 23 Meretoja OA. Neuromuscular blocking agents in paediatric patients: influence of age on the response. Anaesth Intensive Care 1990; 18: 440-448
    CrossrefPubMedSearch in Google Scholar
  • 24 Thilen SR, Weigel WA, Todd MM. et al. 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade: A Report by the American Society of Anesthesiologists Task Force on Neuromuscular Blockade. Anesthesiology 2023; 138: 13-41
    CrossrefPubMedSearch in Google Scholar
  • 25 Cha YM, Faulk DJ. Management of neuromuscular block in pediatric patients – safety implications. Current Anesthesiology Reports 2022; 12: 439-450
    CrossrefPubMedSearch in Google Scholar
  • 26 Owusu-Bediako K, Munch R, Mathias J. et al. Feasibility of intraoperative quantitative neuromuscular blockade monitoring in children using electromyography. Saudi J Anaesth 2022; 16: 412-418
    CrossrefPubMedSearch in Google Scholar
  • 27 Voss T, Wang A, DeAngelis M. et al. Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study. Paediatr Anaesth 2022; 32: 436-445
    CrossrefPubMedSearch in Google Scholar
  • 28 Lang B, Han L, Zeng L. et al. Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis. BMC Pediatr 2022; 22: 295
    CrossrefPubMedSearch in Google Scholar
  • 29 Gaver RS, Brenn BR, Gartley A. et al. Retrospective Analysis of the Safety and Efficacy of Sugammadex Versus Neostigmine for the Reversal of Neuromuscular Blockade in Children. Anesth Analg 2019; 129: 1124-1129
    CrossrefPubMedSearch in Google Scholar
  • 30 Alonso A, de Boer HD, Booij L. Reversal of rocuronium-induced neuromuscular block by sugammadex in neonates: 10AP1–3. Eur J Anaesthesiol 2014; 31: 163
    CrossrefPubMedSearch in Google Scholar
  • 31 Carlos RV, Torres ML, de Boer HD. Rocuronium and sugammadex in a 3 days old neonate for draining an ovarian cyst. Neuromuscular management and review of the literature. Braz J Anesthesiol 2016; 66: 430-432
    PubMedSearch in Google Scholar
  • 32 Matsui M, Konishi J, Suzuki T. et al. Reversibility of Rocuronium-Induced Deep Neuromuscular Block with Sugammadex in Infants and Children-A Randomized Study. Biol Pharm Bull 2019; 42: 1637-1640
    CrossrefPubMedSearch in Google Scholar
  • 33 Lorinc AN, Lawson KC, Niconchuk JA. et al. Residual Weakness and Recurarization After Sugammadex Administration in Pediatric Patients: A Case Series. A A Pract 2020; 14: e01225
    CrossrefPubMedSearch in Google Scholar
  • 34 Kotake Y, Ochiai R, Suzuki T. et al. Reversal with sugammadex in the absence of monitoring did not preclude residual neuromuscular block. Anesth Analg 2013; 117: 345-351
    CrossrefPubMedSearch in Google Scholar