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Endoscopy
DOI: 10.1055/a-2546-4853
Innovations and brief communications

Partial ampullary endoscopic mucosal resection in patients with difficult biliary cannulation: a prospective cohort study

Salih Tokmak 
1   Department of Gastroenterology, Internal Medicine, Duzce University, Duzce, Turkey
,
Mehmet Fuat Cetin
2   General Surgery, Duzce University, Duzce, Turkey
,
Abdullatif Sirin
1   Department of Gastroenterology, Internal Medicine, Duzce University, Duzce, Turkey
,
Sevki Konur
1   Department of Gastroenterology, Internal Medicine, Duzce University, Duzce, Turkey
,
Serkan Torun
1   Department of Gastroenterology, Internal Medicine, Duzce University, Duzce, Turkey
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Abstract

Background

The rescue techniques available for cannulation failure are few in number and have severe limitations. We recently described partial ampullary endoscopic mucosal resection (PA-EMR) as a novel technique for difficult biliary cannulation. We aimed to demonstrate the efficacy and safety of PA-EMR for patients with difficult biliary cannulation in a larger cohort.

Methods

We conducted a prospective cohort study at our tertiary care referral hospital. We recorded demographic factors, procedure-related characteristics, and adverse event rates in patients with difficult biliary cannulation who underwent PA-EMR.

Results

Between June 2021 and June 2022, we performed 1073 consecutive endoscopic retrograde cholangiopancreatography procedures on 962 patients; 40 patients (12 male, 28 female, with a mean age of 68.1 [SD 4] years) had difficult biliary cannulation and underwent PA-EMR. Technical success was 100%, and none of the patients required a second session. None of the patients had an adverse event, and we encountered no 30-day mortality. The most typical indication was bile duct stones (60%; n = 24), followed by periampullary tumors (15%; n = 6). The total procedure time was 923 (range 392–1224) seconds.

Conclusion

PA-EMR was an effective and safe rescue technique in patients with difficult biliary cannulation.



Publication History

Received: 18 October 2024

Accepted after revision: 25 February 2025

Accepted Manuscript online:
25 February 2025

Article published online:
11 April 2025

© 2025. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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