Factors affecting the thermal condensation of carboxylic acids
with amines have been investigated, and an effective protocol for
this waste-minimized, environmentally benign transformation has
been identified. Fourteen examples demonstrate the applicability
of this procedure to aliphatic, aromatic and heteroaromatic carboxylic
acids and primary and secondary aliphatic as well as aromatic amines.
The approach leads to the corresponding amides in good yields.
amides - amines - condensation - molecular
sieves
