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Synthesis 2009(5): 860-863  
DOI: 10.1055/s-0028-1083297
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© Georg Thieme Verlag Stuttgart ˙ New York

Diastereoselective Synthesis of 1,2,3-Trisubstituted Indanes via Rhodium(I)-Catalyzed Tandem Conjugate Additions

Cristina Navarro, Aurelio G. Csákÿ*
Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain
Fax: +34(91)3945030; e-Mail: csaky@quim.ucm.es;
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Publication History

Received 30 July 2008
Publication Date:
19 December 2008 (online)

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Abstract

1,2,3-Trisubstituted indanes are synthesized with high diastereoselectivity in favor of the all-trans products by the reaction of boronic acids with electron-deficient o-divinylbenzenes under rhodium(I) catalysis.

Key words

catalysis - Michael addition - tandem reactions - rhodium - synthesis

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