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Synthesis 2009(4): 587-590  
DOI: 10.1055/s-0028-1083312
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

An Efficient Route to 1-Vinylpyrrole-2-carbaldehydes

Al’bina I. Mikhaleva, Andrey V. Ivanov, Elena V. Skital’tseva, Igor’ A. Ushakov, Alexander M. Vasil’tsov, Boris A. Trofimov*
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 Favorsky Street, 664033 Irkutsk, Russian Federation
Fax: +7(3952)419346; e-Mail: boris_trofimov@irioch.irk.ru;
Further Information

Publication History

Received 9 September 2008
Publication Date:
12 January 2009 (online)

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Abstract

1-Vinylpyrroles are formylated by the N,N-dimethyl­formamide/oxalyl chloride reagent system (CH2Cl2, r.t., 40 min) to give the corresponding 1-vinylpyrrole-2-carbaldehydes in yields up to 97%.

Key words

aldehydes - pyrroles - formylation - oxalyl chloride - Vilsmeier-Haack reaction

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