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DOI: 10.1055/s-0028-1083326
Synthesis and Olfactory Evaluation of (4aR*,8aR*)-1,1,8a-Trimethyl-decahydronaphthalen-4a-ol: A cis-Decalol Intersection Structure of (-)-Patchoulol and (5R*,6S*)-1,1,6-Trimethylspiro[4.5]decan-6-ol
Publikationsverlauf
Publikationsdatum:
26. Januar 2009 (online)
Inadvertently, instead of (-)-patchoulol, the (+)-enantiomer was drawn in Figures [¹] and [²] . As the target compound and all intermediates are racemates, this has no influence on the results, still Figures [¹] and [²] should be replaced by the correct representations below. For the sake of better correlation, the opposite enantiomer has also been delineated for racemic compounds. The authors apologize for this mistake.
![](https://www.thieme-connect.de/media/synthesis/200903/r10309ss_f1.jpg)
Figure 1 Patchouli odorants, decalin odorants, and the derivation of the cis-decalol intersection target structure 4
![](https://www.thieme-connect.de/media/synthesis/200903/r10309ss_f2.jpg)
Figure 2 Biflexible superposition analysis of (-)-patchoulol (1, depicted in silver) on the patchouli-smelling (5R*,6S*)-1,1,6-trimethylspiro[4.5]decan-6-ol (3, displayed in gold) with the MOE 2007.09 software package
![](https://www.thieme-connect.de/media/synthesis/200903/r10309ss_f1.jpg)
Figure 1 Patchouli odorants, decalin odorants, and the derivation of the cis-decalol intersection target structure 4
![](https://www.thieme-connect.de/media/synthesis/200903/r10309ss_f2.jpg)
Figure 2 Biflexible superposition analysis of (-)-patchoulol (1, depicted in silver) on the patchouli-smelling (5R*,6S*)-1,1,6-trimethylspiro[4.5]decan-6-ol (3, displayed in gold) with the MOE 2007.09 software package