Synthesis, Table of Contents PAPER © Georg Thieme Verlag Stuttgart ˙ New York IBX/TBAB-Mediated Oxidation of Primary Amines to Nitriles Fleur Drouet, Patrice Fontaine, Géraldine Masson*, Jieping Zhu*Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, FranceFax: +33(1)69077247; e-Mail: zhu@icsn.cnrs-gif.fr; e-Mail: masson@icsn.cnrs-gif.fr; Recommend Article Abstract Buy Article All articles of this category Abstract The combination of o-iodoxybenzoic acid (IBX) and tetrabutylammonium bromide (TBAB) efficiently oxidizes primary amines to the corresponding nitriles in good to excellent yield under mild conditions. The reaction is racemization-free when applied to a chiral lysine derivative. Key words o-iodoxybenzoic acid (IBX) - tetrabutylammonium bromide (TBAB) - amines - nitriles - oxidation - dehydrogenation Full Text References References 1a The Chemistry of the Cyano Group Rappoport Z. Interscience; New York: 1970. 1b Fatiadi AJ. 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