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DOI: 10.1055/s-0029-1186242
© Georg Thieme Verlag KG Stuttgart · New York
Minimizing Circulatory Arrest by Using Antegrade Cerebral Perfusion for Aortic Arch Reconstruction in Infants Causes Fewer Postoperative Adverse Events
Publication History
received April 26, 2009
Publication Date:
13 January 2010 (online)
![](https://www.thieme-connect.de/media/thoracic/201001/lookinside/thumbnails/10.1055-s-0029-1186242-1.jpg)
Abstract
Background: Because deep hypothermic circulatory arrest (DHCA) carries a risk for neurological damage, antegrade cerebral perfusion (ACP) is used increasingly for aortic arch surgery in infants. We assessed the short-term effects of minimal DHCA (< 30 minutes) versus prolonged DHCA (> 30 minutes) during biventricular aortic arch reconstruction. Methods: Twenty-six infants (< 3 months of age) who had undergone aortic arch reconstruction were retrospectively analyzed: 15 infants without DHCA (group A) and 11 infants with DHCA (group B). Group B was further divided into < 30 minutes DHCA (group B1, n = 6), and ≥ 30 minutes DHCA (group B2, n = 5). Additionally, minimal DHCA (group A + B1) was compared to prolonged DHCA (group B2). Results: In the minimal DHCA group (A + B1), 29 % of the patients had a postoperative adverse event, compared to 80 % in the prolonged DHCA group (B2) (p < 0.05). Average length of stay in hospital was 25 days shorter for the minimal DHCA group (15 days versus 40 days, p < 0.01).
Conclusion: Minimal DHCA results in fewer adverse events and a reduced length of stay, compared with prolonged DHCA. Therefore, during aortic arch surgery in infants, DHCA should be minimized by using antegrade cerebral perfusion.
Key words
antegrade cerebral perfusion - deep hypothermic circulatory arrest - pediatric cardiothoracic surgery
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MD, MSc Jasper Selder
Cardio Thoracic Surgery
University Medical Center Utrecht
Lundlaan 6
3584 EA Utrecht
Netherlands
Email: jappe@jappe.net