C-H Bond Activation:
A Versatile Protocol for the Direct Arylation and Alkenylation
of Oxazoles

François Besselièvre; Sabrina Lebrequier; Florence Mahuteau-Betzer; Sandrine Piguel

doi:10.1055/s-0029-1216987

SPECIALTOPIC

C-H Bond Activation: A Versatile Protocol for the Direct Arylation and Alkenylation of Oxazoles

François Besselièvre^a, Sabrina Lebrequier^b, Florence Mahuteau-Betzer^b, Sandrine Piguel*^a
^a Univ Paris-Sud 11, 91405 Orsay, France
Fax: +33(1)69075381; e-Mail: sandrine.piguel@curie.u-psud.fr;
^b Institut Curie/CNRS, UMR176, Bât. 110, Centre Universitaire, 91405 Orsay, France

Abstract

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Abstract

The versatile palladium complex Pd(PPh₃)₄ catalyses both direct arylation and alkenylation of oxazoles efficiently. The method is regioselective and stereospecific with respect to bromoalkenes and tolerates a wide range of functional groups.

Key words

oxazole - arylation - alkenylation - palladium - C-H activation

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Referenzen

References

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