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Synthesis 2010(9): 1505-1511
DOI: 10.1055/s-0029-1218691
DOI: 10.1055/s-0029-1218691
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkMild Conditions for Copper-Catalyzed N-Arylation of Imidazoles
Further Information
Received
7 December 2009
Publication Date:
09 March 2010 (online)
Publication History
Publication Date:
09 March 2010 (online)
Abstract
An efficient copper(I) bromide catalyzed N-arylation of azoles with a variety of aromatic bromides and iodides under mild conditions is reported. This reaction displayed great functional group compatibility and excellent reactive selectivity.
Key words
copper - aryl halides - imidazoles - azoles - N-arylation
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