Eur J Pediatr Surg 2010; 20(2): 130-131
DOI: 10.1055/s-0029-1234063
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Gastrointestinal Stromal Tumour of the Stomach in a Young Child with Oesophageal Stricture

X. S. Roussis1 , C. A. Hajivassiliou2 , E. Rahmani1 , K. Prodromou1 , T. Podas3 , A. Zavitsanakis1
  • 1Aristotle University of Thessaloniki, 1st Department of Pediatric Surgery, Thessaloniki, Greece
  • 2Royal Hospital for Sick Children, Department of Pediatric Surgery, Glasgow, United Kingdom
  • 3St Luke's Hospital, Gastroenterology, Panorama, Thessaloniki, Greece
Further Information

Publication History

Publication Date:
10 September 2009 (online)

Introduction

Gastrointestinal stromal tumours (GIST) are rare neoplasms of mesenchymal origin. They usually present after the age of 30 and are rare in childhood. They are usually found in the submucosa of the stomach and small bowel and demonstrate a variable spectrum of benign and malignant characteristics with unpredictable behaviour [7]. Upper gastrointestinal bleeding or anaemia is often the presenting symptom. In this case report we describe a male infant who had correction of oesophageal atresia at birth and was found to have a gastric GIST 20 months later at routine endoscopy for oesophageal dilatation.

References

  • 1 Bensimhon D, Soyer P, Brouland JPP. et al . Gastrointestinal stromal tumors: role of computed tomography before and after treatment.  Gastroenterol Clin Biol. 2008;  32 91-97
  • 2 Durham MM, Gow KW, Shehata BM. et al . Gastrointestinal stromal tumors arising from the stomach: a report of three children.  J Pediatr Surg. 2004;  39 1495-1499
  • 3 Hayashi Y, Okazaki T, Yamataka A. et al . Gastrointestinal stromal tumor in a child and review of the literature.  Pediatr Surg Int. 2005;  21 914-917
  • 4 Miettinen M, Lasota J, Sobin LH. Gastrointestinal stromal tumors of the stomach in children and young adults: clinicopathologic, immunohistochemical and molecular genetic study of 44 cases with long-term follow-up and review of the literature.  Am J Surg Pathol. 2005;  29 1373-1381
  • 5 O’Sullivan MJ, McCabe A, Gillett P. et al . Multiple gastric stromal tumors in a child without syndromic association lacks common KIT or PDGFRalpha mutations.  Pediatr Dev Pathol. 2005;  8 685-689
  • 6 Otani Y, Yoshida M, Saikawa Y. et al . Discrimination between gastric ectopic pancreas and mesenchymal tumors, including GIST-from 12 years’ surgical experience in one institute.  Aliment Pharmacol Ther. 2006;  24 292-296
  • 7 Prakash S, Sarran L, Socci N. et al . Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular and genomic study of 15 cases and review of the literature.  J Pediatr Hematol Oncol. 2005;  27 179-187
  • 8 Sauseng W, Benesch M, Lackner H. et al . Clinical, radiological and pathological findings in four children with gastrointestinal stromal tumors of the stomach.  Pediatr Hematol Oncol. 2007;  24 209-219

Correspondence

Dr. Xenofon Stefanos Roussis

28 Dodekanisou Street

Plagiari

57500 Thessaloniki

Greece

Phone: 00306977265947

Fax: 00302310287282

Email: xenos@otenet.gr