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Horm Metab Res 2010; 42(2): 143-148
DOI: 10.1055/s-0029-1241830
Humans, Clinical

© Georg Thieme Verlag KG Stuttgart · New York

Early Infant Diet in Children at High Risk for Type 1 Diabetes

M. Pflüger2 , C. Winkler2 , S. Hummel1 , 2 , A. G. Ziegler1 , 2 , 3
  • 1Forschergruppe Diabetes der Technischen Universität München, Munich, Germany
  • 2Institut für Diabetesforschung der Forschergruppe Diabetes e.V. am Helmholtz Zentrum München, Munich, Germany
  • 3Klinik für Endokrinologie, Diabetologie und Suchtmedizin, Klinikum Schwabing StKM, Munich, Germany
Further Information

Publication History

received 29.04.2009

accepted 08.10.2009

Publication Date:
09 November 2009 (online)

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Abstract

Infant diet affects health and development. The aim of our study was to investigate WHO infant feeding compliance in children who have a first degree family history of type 1 diabetes (T1D). One hundred and fifty children who were first degree relatives of patients with T1D were intensively followed from birth in the BABYDIET intervention study. Infant feeding, infections, and medication were recorded daily by participating families. Weight and length of children were obtained from paediatric records. Only 5% of the families followed the WHO recommendations for infant feeding that include full breastfeeding for at least 6 months (18.8% of children) and introduction of complementary foods under continued breastfeeding thereafter (22.2% of children). Maternal age in the first quartile (<29 years; p<0.0001), and maternal smoking (p<0.0001) were associated with an earlier introduction of solid food and reduced breastfeeding. Full breastfeeding ≥6 months was associated with reduced frequency of gastrointestinal infections (12 vs. 38%, p=0.02) and antibiotic treatment (24 vs. 48%, p=0.04). Our findings indicate that WHO infant feeding recommendations were poorly followed by families with a family history of T1D. Action to improve levels of infant feeding behaviour is essential, especially among young mothers with T1D.

Key words

diabetes mellitus - infant feeding - breastfeeding - infections - antibiotic treatment

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Correspondence

Prof. Dr. A. G. Ziegler

Forschergruppe Diabetes

Technische Universität München

Kölner Platz 1

80804 Munich

Germany

Phone: +49 89 306 82591

Fax: +49 89 306 97509

Email: anziegler@lrz.uni-muenchen.de