RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000049.xml
PDF herunterladen
Clin Colon Rectal Surg 2009; 22(4): 242-250
DOI: 10.1055/s-0029-1242464
© Thieme Medical PublishersDOI: 10.1055/s-0029-1242464
Surveillance after Curative Resection of Colorectal Cancer
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
06. November 2009 (online)
ABSTRACT
Surgical resection is the primary treatment modality for patients with localized colorectal cancer, but unfortunately one-third to one-half of these patients will develop a recurrence. If detected early, recurrent disease may be amenable to surgical resection and this provides the rationale for a follow-up strategy in patients with resected colorectal cancer. Despite eight published randomized controlled trials and six published systematic reviews evaluating different follow-up strategies, there is still no consensus as to the appropriateness of follow-up in colorectal cancer patients. In the present article the authors explore the reasons behind the controversy and the arguments used to support each side. They outline the current published guidelines and the data to support these recommendations, including the use of carcinoembryonic antigen (CEA) levels, liver imaging, and colonoscopy. Finally, they speculate on the future developments that may impact on this debate.
KEYWORDS
Colorectal neoplasm - postoperative surveillance - colorectal surgery
REFERENCES
- 1 Böhm B, Schwenk W, Hucke H P, Stock W. Does methodic long-term follow-up affect survival after curative resection of colorectal carcinoma?. Dis Colon Rectum. 1993; 36(3) 280-286
- 2 Mäkelä J T, Laitinen S O, Kairaluoma M I. Five-year follow-up after radical surgery for colorectal cancer. Results of a prospective randomized trial. Arch Surg. 1995; 130(10) 1062-1067
- 3 Ohlsson B, Breland U, Ekberg H, Graffner H, Tranberg K G. Follow-up after curative surgery for colorectal carcinoma. Randomized comparison with no follow-up. Dis Colon Rectum. 1995; 38(6) 619-626
- 4 Kjeldsen B J, Kronborg O, Fenger C, Jørgensen O D. A prospective randomized study of follow-up after radical surgery for colorectal cancer. Br J Surg. 1997; 84(5) 666-669
- 5 Pietra N, Sarli L, Costi R, Ouchemi C, Grattarola M, Peracchia A. Role of follow-up in management of local recurrences of colorectal cancer: a prospective, randomized study. Dis Colon Rectum. 1998; 41(9) 1127-1133
- 6 Schoemaker D, Black R, Giles L, Toouli J. Yearly colonoscopy, liver CT, and chest radiography do not influence 5-year survival of colorectal cancer patients. Gastroenterology. 1998; 114(1) 7-14
- 7 Secco G B, Fardelli R, Gianquinto D et al.. Efficacy and cost of risk-adapted follow-up in patients after colorectal cancer surgery: a prospective, randomized and controlled trial. Eur J Surg Oncol. 2002; 28(4) 418-423
- 8 Grossmann E M, Johnson F E, Virgo K S, Longo W E, Fossati R. Follow-up of colorectal cancer patients after resection with curative intent-the GILDA trial. Surg Oncol. 2004; 13(2-3) 119-124
- 9 Rodríguez-Moranta F, Saló J, Arcusa A et al.. Postoperative surveillance in patients with colorectal cancer who have undergone curative resection: a prospective, multicenter, randomized, controlled trial. J Clin Oncol. 2006; 24(3) 386-393
- 10 Tjandra J J, Chan M K. Follow-up after curative resection of colorectal cancer: a meta-analysis. Dis Colon Rectum. 2007; 50(11) 1783-1799
- 11 Jeffery M, Hickey B E, Hider P N. Follow-up strategies for patients treated for non-metastatic colorectal cancer. Cochrane Database Syst Rev. 2007; (1) CD002200
- 12 Figueredo A, Rumble R B, Maroun J Gastrointestinal Cancer Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care et al. Follow-up of patients with curatively resected colorectal cancer: a practice guideline. BMC Cancer. 2003; 3 26
- 13 Renehan A G, Egger M, Saunders M P, O'Dwyer S T. Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials. BMJ. 2002; 324(7341) 813
- 14 Renehan A G, Egger M, Saunders M P, O'Dwyer S T. Mechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis. Br J Cancer. 2005; 92(3) 430-433
- 15 Renehan A G, O'Dwyer S T, Whynes D K. Cost effectiveness analysis of intensive versus conventional follow up after curative resection for colorectal cancer. BMJ. 2004; 328(7431) 81
- 16 Goldberg R M, Fleming T R, Tangen C M et al.. Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Eastern Cooperative Oncology Group, the North Central Cancer Treatment Group, and the Southwest Oncology Group. Ann Intern Med. 1998; 129(1) 27-35
- 17 Bruinvels D J, Stiggelbout A M, Kievit J, van Houwelingen H C, Habbema J D, van de Velde C J. Follow-up of patients with colorectal cancer. A meta-analysis. Ann Surg. 1994; 219(2) 174-182
- 18 Rosen M, Chan L, Beart Jr R W, Vukasin P, Anthone G. Follow-up of colorectal cancer: a meta-analysis. Dis Colon Rectum. 1998; 41(9) 1116-1126
- 19 Audisio R A, Robertson C. Colorectal cancer follow-up: perspectives for future studies. Eur J Surg Oncol. 2000; 26(4) 329-337
- 20 Edelman M J, Meyers F J, Siegel D. The utility of follow-up testing after curative cancer therapy. A critical review and economic analysis. J Gen Intern Med. 1997; 12(5) 318-331
- 21 Desch C E, Benson III A B, Somerfield M R American Society of Clinical Oncology et al. Colorectal cancer surveillance: 2005 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol. 2005; 23(33) 8512-8519
- 22 Practice NCCN .Guidelines in Oncology. National Comprehensive Cancer Network, 2009. Available at: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp Accessed June 5, 2009
- 23 Scholefield J H, Steele R J. British Society For Gastroenterology . Guidelines for follow up after resection of colorectal cancer. Gut. 2002; 51(Suppl 5) V3-V5
- 24 Van Cutsem E J, Oliveira J. ESMO Guidelines Working Group . Colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up. Ann Oncol. 2008; 19(Suppl 2) ii29-ii30
- 25 Galandiuk S, Wieand H S, Moertel C G et al.. Patterns of recurrence after curative resection of carcinoma of the colon and rectum. Surg Gynecol Obstet. 1992; 174(1) 27-32
- 26 Stiggelbout A M, de Haes J C, Vree R et al.. Follow-up of colorectal cancer patients: quality of life and attitudes towards follow-up. Br J Cancer. 1997; 75(6) 914-920
- 27 Kiebert G M, Welvaart K, Kievit J. Psychological effects of routine follow up on cancer patients after surgery. Eur J Surg. 1993; 159(11-12) 601-607
- 28 Mayer R J, Garnick M B, Steele Jr G D, Zamcheck N. Carcinoembryonic antigen (CEA) as a monitor of chemotherapy in disseminated colorectal cancer. Cancer. 1978; 42(3, Suppl) 1428-1433
- 29
Glover C, Douse P, Kane P et al..
Accuracy of investigations for asymptomatic colorectal liver metastases.
Dis Colon Rectum.
2002;
45(4)
476-484
MissingFormLabel
- 30 Moertel C G, Fleming T R, Macdonald J S, Haller D G, Laurie J A, Tangen C. An evaluation of the carcinoembryonic antigen (CEA) test for monitoring patients with resected colon cancer. JAMA. 1993; 270(8) 943-947
- 31 Goldstein M J, Mitchell E P. Carcinoembryonic antigen in the staging and follow-up of patients with colorectal cancer. Cancer Invest. 2005; 23(4) 338-351
- 32 Arriola E, Navarro M, Parés D et al.. Imaging techniques contribute to increased surgical rescue of relapse in the follow-up of colorectal cancer. Dis Colon Rectum. 2006; 49(4) 478-484
- 33 Chau I, Allen M J, Cunningham D et al.. The value of routine serum carcino-embryonic antigen measurement and computed tomography in the surveillance of patients after adjuvant chemotherapy for colorectal cancer. J Clin Oncol. 2004; 22(8) 1420-1429
- 34 Winawer S J, Zauber A G, O'Brien M J The National Polyp Study Workgroup et al. Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. N Engl J Med. 1993; 328(13) 901-906
- 35 Griffin M R, Bergstralh E J, Coffey R J, Beart Jr R W, Melton III L J. Predictors of survival after curative resection of carcinoma of the colon and rectum. Cancer. 1987; 60(9) 2318-2324
- 36 Enblad P, Adami H O, Glimelius B, Krusemo U, Påhlman L. The risk of subsequent primary malignant diseases after cancers of the colon and rectum. A nationwide cohort study. Cancer. 1990; 65(9) 2091-2100
- 37 Kjeldsen B J, Thorsen H, Whalley D, Kronborg O. Influence of follow-up on health-related quality of life after radical surgery for colorectal cancer. Scand J Gastroenterol. 1999; 34(5) 509-515
- 38 Borie F, Combescure C, Daurès J P, Trétarre B, Millat B. Cost-effectiveness of two follow-up strategies for curative resection of colorectal cancer: comparative study using a Markov model. World J Surg. 2004; 28(6) 563-569
- 39 Spratlin J L, Hui D, Hanson J, Butts C, Au H J. Community compliance with carcinoembryonic antigen: follow-up of patients with colorectal cancer. Clin Colorectal Cancer. 2008; 7(2) 118-125
- 40 Cheung W Y, Pond G R, Rother M et al.. Adherence to surveillance guidelines after curative resection for stage II/III colorectal cancer. Clin Colorectal Cancer. 2008; 7(3) 191-196
- 41 Grossmann I, de Bock G H, van de Velde C J, Kievit J, Wiggers T. Results of a national survey among Dutch surgeons treating patients with colorectal carcinoma. Current opinion about follow-up, treatment of metastasis, and reasons to revise follow-up practice. Colorectal Dis. 2007; 9(9) 787-792
- 42 Giordano P, Efron J, Vernava III A M, Weiss E G, Nogueras J J, Wexner S D. Strategies of follow-up for colorectal cancer: a survey of the American Society of Colon and Rectal Surgeons. Tech Coloproctol. 2006; 10(3) 199-207
- 43 Cardella J, Coburn N G, Gagliardi A et al.. Compliance, attitudes and barriers to post-operative colorectal cancer follow-up. J Eval Clin Pract. 2008; 14(3) 407-415
- 44 Cheah L P, Hemingway D M. Improving colorectal cancer follow-up: the dedicated single-visit colorectal cancer follow-up clinic. Ann R Coll Surg Engl. 2002; 84(4) 260-262
- 45 Renehan A G, Wille-Jørgensen P. Towards a more prescriptive follow-up regimen for colorectal cancer. Colorectal Dis. 2006; 8(8) 623-625
- 46 Fernandez F G, Drebin J A, Linehan D C, Dehdashti F, Siegel B A, Strasberg S M. Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET). Ann Surg. 2004; 240(3) 438-447 discussion 447-450
- 47 Fong Y, Saldinger P F, Akhurst T et al.. Utility of 18F-FDG positron emission tomography scanning on selection of patients for resection of hepatic colorectal metastases. Am J Surg. 1999; 178(4) 282-287
- 48 Shen Y Y, Liang J A, Chen Y K, Tsai C Y, Kao C H. Clinical impact of 18F-FDG-PET in the suspicion of recurrent colorectal cancer based on asymptomatically elevated serum level of carcinoembryonic antigen (CEA) in Taiwan. Hepatogastroenterology. 2006; 53(69) 348-350
- 49 Flanagan F L, Dehdashti F, Ogunbiyi O A, Kodner I J, Siegel B A. Utility of FDG-PET for investigating unexplained plasma CEA elevation in patients with colorectal cancer. Ann Surg. 1998; 227(3) 319-323
Rebecca Ann C AuerM.D.
Surgical Oncology and Colorectal Surgery, Ottawa Health Research Institute, University
of Ottawa, Ottawa Hospital–General Campus
501 Smyth Rd., CCW 1617, Ottawa, ON, K1H 8L6 Canada
eMail: rauer@ohri.ca