Chemical Composition and Seasonal Variations in the Amount of Secondary Compounds in Gentiana lutea Leaves and Flowers

Abstract

The chemical investigation of MeOH extracts of Gentiana lutea leaves and flowers showed that xanthones were one of the dominant class of compounds. Secoiridoids and flavonoids were also recorded. The amount of secondary metabolites varied depending on development stage. In the phase of flowering, leaves are rich with compounds possessing C-glycoside structures while O-glycoside structures accumulate mainly before flowering.

References

• 1 Wichtl M. In: Teedrogen, (Wichtl M, ed.) Stuttgart; Scientific Publishers 1994: pp. 233-235
• 2 Hostettmann K, Bellmann G, Tabacci R, Jacot-Guillarmd A. Helv Chim Acta 1973 56: 3050-3055
• 3 Suzuki O, Katsumata Y, Oya M. Biochemical Pharmacology 1978 27: 2075-2078
• 4 Bakuridze A D, Cagareišvili N T, Dargaeva T D, Patudin A V, Berašvili D T. Rast Resursi 1991 27: 115-119
• 5 Ghosal S, Rao G, Saravanan V, Misro N, Rana D. Ind J Organ Chem 1996 35: 561-566
• 6 Born M, Carrupt P A, Zini R, Bree F, Tillement J P, Hostettmann K, Testa B. Helv Chim Acta 1996 79: 1147-1158
• 7 Ghosal S, Chaudhuri R K. J Pharm Sci 1975 64: 888-889
• 8 Bhattacharya S K, Ghosal S, Chadhuri R K, Sanyal A K. J Pharm Sci 1972 61: 1838-1840
• 9 Demizu S, Ohshima Y, Hiraga Y, Takahashi K. J Chromatogr 1986 360: 307-311
• 10 Hostettmann K, Domon B, Schaufelberger D, Hostettmann M. J Chromatogr 1984 283: 137-147
• 11 Nikolaev S M, Bakuridze A D, Dargaeva T D, Brutko L I, Patudin A V, Schagzhieva G A, Nikolaeva G G. Izv Sib Otd Akad Nauk URSS Ser Biol Nauk 1987 0 (3) (in Russian)
• 12 Glizin V I, Bankovski A I, Pimenov M T, Borev K I. Him Prirod Soed 1973 4: 434-437 (in Russian)
• 13 Nikolaeva G G, Glizin V I, Mladenceva M S. Him Prirod Soed 1983 1: 107-108 (in Russian)
• 14 Menkovič N. Ph D Thesis University of Belgarde, Faculty of Pharmacy 1997