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Thorac Cardiovasc Surg 2011; 59(2): 128-130
DOI: 10.1055/s-0030-1250086
Case Reports/Thoracic

© Georg Thieme Verlag KG Stuttgart · New York

Pulmonary Epithelioid Hemangioendothelioma with PlGF Expression: Report of a Case

T. Haruki1 , T. Arai1 , H. Nakamura1 , K. Nosaka2 , K. Shomori2 , H. Ito2
  • 1General Thoracic Surgery, Tottori University Hospital, Yonago, Japan
  • 2Department of Microbiology and Pathology, Faculty of Medicine, Tottori University, Yonago, Japan
Further Information

Publication History

received February 18, 2010

Publication Date:
07 March 2011 (online)

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Abstract

Pulmonary epithelioid hemangioendothelioma (PEH) is a relatively uncommon neoplasm of vascular origin with a low or intermediate grade of malignancy. We present a case of a 28-year-old female with multiple pulmonary nodules which were diagnosed as PEH by video-assisted thoracoscopic surgery (VATS) biopsy. In addition, we performed an immunohistochemical analysis for placenta growth factor (PlGF) and a strong positivity for PlGF observed, suggesting that the PlGF may play some role in the tumorigenesis of PEH.

Key words

Thoracic surgery - pulmonary epithelioid hemangioendothelioma (PEH) - video‐assisted thoracoscopic surgery (VATS) - placenta growth factor (PlGF) - vascular endothelial growth factor (VEGF)

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Dr. Tomohiro Haruki

General Thoracic Surgery
Tottori University Hospital

36-1 Nishi-machi

683-8504 Yonago

Japan

Phone: +81 8 59 38 67 37

Fax: +81 8 59 38 67 30

Email: tharuki@med.tottori-u.ac.jp