Cardiac Defect with Diaphragmatic Hernia and Left Lung Agenesis – Heart Disease and Other Anomalies

Abstract

This report describes a rare case of left pulmonary agenesis associated with congenital diaphragmatic hernia and congenital heart disease in a 2-year-old child with pulmonary hypertension. We performed direct radical correction of the congenital heart defect. The postoperative course was challenging but without major complications.

Key words

Cardiovascular surgery - thoracic surgery - heart disease - congenital heart disease - lung agenesis‐diaphragmatic hernia - sildenafil

References

• 1 Graziano J N Congenital Diaphragmatic Hernia Study Group for the . Cardiac anomalies in patients with congenital diaphragmatic hernia and their prognosis: a report from the Congenital Diaphragmatic Hernia Study Group.  Journal of Pediatric Surgery. 2005;  40 1045-1050
• 2 Finci V, Begbetti M, Kalangos A, Brundler M A. Unilateral total and contralateral partial pulmonary agenesis associated with total anomalous pulmonary venous drainage.  J Pediatr. 1999;  134 510-512
• 3 Ishikawa K, Hoshino S, Iwaya F, Ono T, Sato K, Misawa Y. A case of ventricular septal defect and atrial septal defect in an infant with right lung aplasia.  Jpn J Cardiovasc Surg. 1999;  28 163-166
• 4 Buzzarro M, Gross I. Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease.  Anesth Analg. 2006;  102 (3) 964
• 5 Mikhail G W, Prasad S K, Li W, Rogers P, Chester A H, Bayne S, Stephens D, Khan M, Gibbs J S R, Evans T W, Mitchell A, Yacoub M H, Gatzoulis M A. Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mid-term effects.  European Heart Journal. 2004;  25 431-436
• 6 Sastry B K, Narasimhan C, Reddy N K, Raju B S. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study.  J Am Coll Cardiol. 2004;  43 1149-1153