Zusammenfassung
Die Zunahme von Adipositas und ihrer Folgeerkrankungen, insbesondere Typ-2-Diabetes,
erfordert die Intensivierung aller bekannten präventiven und therapeutischen Maßnahmen.
Hierzu zählen bei Adipositas Grad 3 neben den konservativen Programmen gegebenenfalls
auch adipositaschirurgische (bariatrische) Operationen. Typ-2-Diabetiker profitieren
überproportional, da sich unmittelbar nach insbesondere malabsorptiven Operationsverfahren
die Stoffwechsellage dramatisch bessert, und zwar unabhängig von der erst im Laufe
von Wochen und Monaten beobachteten Gewichtsabnahme. Langzeitstudien mit bis zu 15
Jahren Follow-up belegen den nachhaltigen positiven Effekt bariatrischer Operationen
auf Gewichtsverlust, adipositasassoziierte Erkrankungen und Mortalität. Die Arbeitsgruppe
Adipositas des BDEM (Bundesverband Deutscher Ernährungsmediziner e. V.) hat einen
Behandlungspfad zur Therapie von Personen mit massiver Adipositas entwickelt.
Increasing adiposity and its subsequent diseases, especially Type 2 diabetes, makes
it necessary to intensify all the well-known preventive and therapeutic measures.
These include, in case of grade 3 adiposity, not only the conservative programmes
but also whenever necessary bariatric surgery (adipose patient surgery). This will
super-proportionally benefit Type 2 diabetics, since there is an immediate dramatic
improvement in the metabolic condition of the patients especially subsequent to malabsorption
surgery, independent of the weight loss. The persistently positive effect of bariatric
surgery has been established with regard to weight loss, adiposity-associated diseases
and mortality, by means of long-term studies with a follow-up of up to 15 years. A
guideline for the treatment of highly adipose patients has been compiled by the Federal
German Association of Physicians Engaged in Nutritional Medicine.
Key words
Diabetes mellitus - massive adiposity - bariatric surgery
Literatur
- 1
Busetto L et al..
Weight loss and postoperative complications in morbidly obese patients with binge
eating disorder treated by laparoscopic adjustable gastric banding.
Obes Surg.
2005;
15
195-201
- 2
International Federation for the Surgery of Obesity. .
Statement on patient selection for bariatric surgery.
Obes Surg.
1997;
7
41
- 3
Schilling-Massmann B et al..
Adipositastherapie bei massiv adipösen Patienten.
Ernährungs Umschau.
2009;
4
246-247
- 4
Mechanick JI et al..
AACE/TOS/ASMBS Bariatric Surgery Guidelines.
Endocr Pract.
2008;
14
(S 01)
1-83
- 5
Fried M et al..
Inter-disciplinary European guidelines on surgery of severe obesity.
Int J of Obes.
2007;
31
1-9
- 6 Weiner R et al.. Adipositaschirurgie.. München: Urban & Fischer Verlag; 2010
- 7
Almogy G et al..
Longitudinal gastrectomy as a treatment for the high-risk super-obese patient.
Obes Surg.
2004;
14
492-497
- 8
Lancaster RT et al..
Bands and bypasses: 30-day morbidity and mortality of bariatric surgical procedures
as assessed by prospective, multi-center, risk-adjusted ACS-NSQIP data.
Surg Endosc.
2008;
22
2554-2563
- 9
Jan J et al..
Comparative study between laparoscopic adjustable gastric banding and laparoscopic
gastric bypass: single-institution, 5-year experience in bariatric surgery.
Surg Obes Relat Dis.
2007;
3
42-50
- 10
Buchwald H et al..
Trends in mortality in bariatric surgery: a systematic review and meta-analysis.
Surgery.
2007;
142
621-632
- 11
Buchwald H et al..
Bariatric surgery: a systematic review and metaanalysis.
JAMA.
2004;
292
1724-1737
- 12
Sjoström L et al..
Reduction in incidence of diabetes, hypertension and lipid disturbances after intentional
weight loss induced by bariatric surgery: the SOS Intervention Study.
Obes Res.
1999;
7
477-484
- 13
Sjoström L et al..
Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery.
N Engl J Med.
2004;
351
2683-2693
- 14
Sjoström L et al..
Effects of bariatric surgery on mortality in Swedish obese subjects.
N Engl J Med.
2007;
357
741-752
- 15
Dixon JB et al..
Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized
controlled trial.
JAMA.
2008;
299
316-323
- 16
Aggarwal S et al..
Laparoscopic sleeve gastrectomy for morbid obesity: a review.
Surg Obes Relat Dis.
2007;
3
189-194
- 17
Pories WJ et al..
Who would have thought it? An operation proves to be the most effective therapy for
adult-onset diabetes mellitus.
Ann Surg.
1995;
222
339-350
- 18
Herbst CA et al..
Gastric bariatric operation in insulin-treated adults.
Surgery.
1984;
95
209-214
- 19
Long SD et al..
Weight loss in severely obese subjects prevents the progression of impaired glucose
tolerance to type II diabetes. A longitudinal interventional study.
Diabetes Care.
1994;
17
372-375
- 20
Narbro K et al..
Economic consequenses of sick-leave and eartly retirement in obese Swedish women.
Int J Obes.
1996;
20
895-903
- 21
Herpertz S et al..
Does obesity surgery improve psychosocial functioning? A systematic review.
Int J Obes Relat Metab Disord.
2003;
27
1300-1314
- 22
Herpertz S et al..
Do psychosocial variables predict weight loss or mental health after obesity surgery?
A systematic review.
Obes Res.
2004;
12
1554-1569
- 23
de Zwaan M et al..
Essverhalten vor und nach adipositaschirurgischer Behandlung.
Aktuelle Ernährungsmedizin.
2009;
34
83-87
- 24
MacDonald KG et al..
The gastric bypass operation reduces the progression and mortality of non-insulin-dependent
diabetes mellitus.
J Gastrointest Surg.
1997;
1
213-220
- 25
Harper J et al..
What happens to patients who do not follow-up after bariatric surgery?.
Am Surg.
2007;
73
181-184
- 26
Orth WS et al..
Support group meeting attendance is associated with better weight loss.
Obes Surg.
2008;
18
391-394
- 27
Ridley N et al..
Expert panel on weight loss surgery: Executive report.
Obes Res.
2005;
13
206-226
- 28
Gasteyger C et al..
Nutritional deficiencies after Roux-en-Y gastric bypass for morbid obesity often cannot
be prevented by standard multivitamin supplementation.
Am J Clin Nutr.
2008;
87
1128-1133
- 29
Coupaye M et al..
Nutritional consequences of adjustable gastric banding and gastric bypass: a 1-year
prospective study.
Obes Surg.
2009;
19
56-65
- 30
Schilling-Massmann B, Keuthage W..
Extrabudgetäre Kostenerstattung für ernährungsmedizinische Vor- und Nachsorge bei
hochgradiger Adipositas.
Ernährungsumschau.
2010;
57
- 31
Christou NV et al..
Surgery decreases long-term mortality, morbidity, and health care use in morbidly
obese patients.
Ann Surg.
2004;
240
416-423
- 32
Rand CS et al..
Surgery for obesity and marriage quality.
JAMA.
1982;
247
1419-1422
Korrespondenz
Dr. med. Winfried Keuthage
Diabetologische Schwerpunkt-praxis Schwerpunktpraxis Ernährungsmedizin
Düesbergweg 128
48153 Münster
eMail: dr@keuthage.de