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Synfacts 2010(9): 1021-1021  
DOI: 10.1055/s-0030-1257946
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Asymmetric Conjugate Addition of Cyanide to Give Quaternary Stereocenters

Contributor(s):Mark Lautens, Stephen G. Newman
Y. Tanaka, M. Kanai*, M. Shibasaki*
The University of Tokyo, Japan
Catalytic Enantioselective Construction of β-Quaternary Carbons via a Conjugate Addition of Cyanide to β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds
J. Am. Chem. Soc.  2010,  132:  8862-8863