A systematic study of the reaction conditions for the preparation
of pure aryl-H-phosphinate esters, originally developed by Sander
and optimized by Petneházy, is reported. The influence of
the reaction concentration has been investigated for the formation of
phosphonite intermediates via direct addition of triethyl phosphite
to the appropriate Grignard reagent. Subsequent hydrolysis of the
phosphonites under acidic conditions gives various aryl-H-phosphinates
in high yields and purities.
phosphonites - phosphinates - aryl-H-phosphinates - triethyl phosphite - hydrolysis - Grignard
reagent
