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Zeitschrift für Phytotherapie 2010; 31(5): 247-250
DOI: 10.1055/s-0030-1262396
Forschung
Restless-legs-Syndrom
© Hippokrates Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Das Restless-legs-Syndrom (RLS) – Erfahrungsbericht mit einem Vitex agnus-castus (VAC)-Extrakt

Axel Brattström, Wolf-Dietrich Kaiser
Further Information

Publication History

Publication Date:
08 November 2010 (online)

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Zusammenfassung

Ethanolische Extrakte der Früchte von Vitex agnus-castus (VAC) wirken als gemischter Dopamin-D2/D3-Rezeptoragonist. Das RLS wird therapiert mit Dopaminagonisten. Ein erster Therapieversuch mit einem standardisierten VAC-Extrakt, d.h. mit einem pflanzlichen Dopaminagonisten, an einer kleinen Patientenzahl (n = 12) ergab vielversprechende Ergebnisse, die durch systematische Untersuchungen zu verifizieren sind.

Summary

The restless legs syndrome. First experiences with an extract from Vitex agnus-castus Ethanolic extracts from the fruits of Vitex agnus-castus (VAC) act as a mixed D2/D3 receptor agonist. Dopamine agonists are first line therapy for restless legs syndrome (RLS). In a small group of patients (n = 12) suffering from RLS a standardized VAC extract was tested as a dopamine agonist derived from plants for the first time. The outcome is promising and further clinical trials should be stimulated.

Schlüsselwörter

Vitex agnus-castus L. - gemischter Dopaminagonist - Restless-legs-Syndrom - Erfahrungsbericht

Key words

Vitex agnus-castus L. - mixed dopamine agonist - restless legs syndrome - clinical experience - off-label use

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Prof. Dr. Axel Brattström



Alexander Puschkin Str. 50

39108 Magdeburg

Email: Axel.Brattstroem@t-online.de

Priv.-Doz. Dr. Wolf-Dietrich Kaiser



Nordhäuser Str. 1

99089 Erfurt

Email: info@doktor-kaiser.de

Online

http://dx.doi.org/10.1055/s-0030-1262396