Zusammenfassung
Sugammadex reversiert die Wirkung von Rocuronium durch Enkapsulierung ohne muskarinerge
Nebenwirkungen. Bisherige publizierte Studien zeigen eine effektive dosisabhängige
Reversierung der neuromuskulären Blockade nach Verwendung von Rocuronium oder Vecuronium.
Wir berichten in unserem Fallbericht von einem Patienten, der am Ende der OP nach
RSI mit Rocuronium eine tiefe neuromuskuläre Blockade zeigte, die innerhalb weniger
Minuten nebenwirkungsfrei reversiert werden konnte.
Abstract
Sugammadex can reverse rocuronium-induced muscular relaxation by encapsulation of
steroidal muscle relaxants without muscarinergic side effects. Clinical studies show
effective dose-dependent reversal of neuromuscular blockades after rocuronium and
vecuronium. We report on a patient with deep neuromuscular block at the end of surgery
following rapid sequence induction of anesthesia with high-dose rocuronium, who could
rapidly be reversed without side effects after adequate i.v. sugammadex application.
Schlüsselwörter
neuromuskuläre Blockade - Rocuronium - Sugammadex - Muskelrelaxans - postoperative
Restcurarisierung - Rapid Sequence Induction
Key words:
muscle relaxant - neuromuscular block - sugammadex - rocuronium - rapid sequence induction
- postoperative residual neuromuscular block
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Dr. med. Christian Adam Prof. Dr. med. Thomas Standl
eMail: adam@klinikumsolingen.de
eMail: standl@klinikumsolingen.de