Semin Thromb Hemost 2011; 37(2): 106-110
DOI: 10.1055/s-0030-1270335
© Thieme Medical Publishers

Thrombophilia and Pre-Eclampsia

Moniek P.M de Maat1 , Christianne J.M de Groot1
  • 1Department of Hematology, Erasmus University Medical Center, Rotterdam and Obstetrics and Gynaecology, VU University, Amsterdam, Medical Center, The Netherlands
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
02. März 2011 (online)

Preview

ABSTRACT

Pre-eclampsia (P-EC) poses an increased risk for fetal and maternal morbidity and sometimes even mortality. Several risk factors have been identified, among which an important extensively studied group is formed by the early recognizable genetic factors resulting in thrombophilia. The discussion is ongoing whether the associations found for thrombophilia are true and clinically relevant. In this review, we address the association between P-EC and thrombophilia, its concerns, and the necessity of screening after a pregnancy complicated by hypertension.

REFERENCES

Moniek P.M de MaatPh.D. 

Department of Hematology, L-431, Erasmus MC

P.O. Box 2040, 3000 CA Rotterdam, The Netherlands

eMail: m.demaat@erasmusmc.nl