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DOI: 10.1055/s-0030-1271028
© Georg Thieme Verlag KG Stuttgart · New York
Long-term Results of Mechanical and Biological Heart Valves in Dialysis and Non-Dialysis Patients
Publication History
received February 4, 2011
revised March 8, 2011
accepted March 10, 2011
Publication Date:
03 May 2011 (online)
![](https://www.thieme-connect.de/media/thoracic/201108/lookinside/thumbnails/10.1055-s-0030-1271028-1.jpg)
Abstract
Introduction: We wanted to answer the question whether biological heart valves are inferior compared to mechanical heart valves in end-stage renal disease (ESRD) patients. Methods: Between 01/1996 und 12/2006, 44 of 3293 patients undergoing aortic valve replacement (AVR) in a single institution suffered from dialysis-dependent ESRD and underwent a follow-up investigation after 1.9 years (median). Twelve (28.9 %) of these patients received a biological, 32 (71.1 %) of these patients a mechanical aortic valve prosthesis. To evaluate a possible influence of the valve type (biological/mechanical) on survival, uni- and multivariate logistic regression was used. Results: ESRD patients after AVR had a relatively poor short-term (30-day mortality: 22.7 %) and long-term survival (median survival time: 24.7 months; 95 % CI: 0.2–47.7 months), irrespective of the type of heart valve prosthesis (hazard ratio for mortality depending on heart valve type in dialysis patients: 1.31, p = 0.400). Dialysis-dependent patients were not reoperated due to valve-related reasons. Conclusions: The long-term survival of dialysis-dependent patients after AVR is low (5-year survival: 29.5 %) irrespective of the type of heart valve prosthesis. Therefore, the use of biological AVR is not contraindicated in this group of patients.
Key words
kidney (includes related subject matter) - heart valve surgery - cardiac - dialysis - end-stage renal disease - aortic valve replacement - biological aortic valve prosthesis - mechanical aortic valve prosthesis - long-term survival - mortality risk factors
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Prof. Andreas Böning, MD, PHD
Department of Cardiovascular Surgery
University Hospital Giessen
Rudolf-Buchheim-Str. 7
35385 Giessen
Germany
Phone: +49 6 41 98 54 43 00
Fax: +49 6 41 98 54 43 09
Email: andreas.boening@chiru.med.uni-giessen.de