DMW - Deutsche Medizinische Wochenschrift, Inhaltsverzeichnis Dtsch Med Wochenschr 2011; 136(16): 847-849DOI: 10.1055/s-0031-1272569 Kommentar | Commentary Kardiologie © Georg Thieme Verlag KG Stuttgart · New York Kardiale Resynchronisationstherapie bei asymptomatischen Patienten mit schwer eingeschränkter linksventrikulärer Funktion Cardiac resynchronisation therapy in asymptomatic patients with severely depressed left ventricular functionC. Stellbrink1 1Klinik für Kardiologie und Internistische Intensivmedizin, Städtische Kliniken Bielefeld Artikel empfehlen Abstract Artikel einzeln kaufen Schlüsselwörter linksventrikuläre Dysfunktion - kardiale Resynchronisationstherapie - Herzinsuffizienz - biventrikuläre Stimulation Keywords left ventricular dysfunction - cardiac resynchronization therapy - heart failure - biventricular stimulation Volltext Referenzen Literatur 1 Auricchio A, Stellbrink C, Sack S. et al . Pacing Therapies in Congestive Heart Failure (PATH-CHF) Study Group. Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. J Am Coll Cardiol. 2002; 39 2026-2033 2 Bänsch D, Antz M, Boczor S, Volkmer M, Tebbenjohanns J, Seidl K, Block M, Gietzen F, Berger J, Kuck K H. Primary prevention of sudden cardiac death in idiopathic dilated cardiomyopathy: the Cardiomyopathy Trial (CAT). Circulation. 2002; 105 1453-1458 3 Bardy G H, Lee K L, Mark D B. et al . Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med. 2005; 352 225-237 4 Brignole M, Gammage M, Puggioni E. et al, on behalf of the Optimal Pacing SITE (OPSITE) Study Investigators . Comparative assessment of right, left, and biventricular pacing in patients with permanent atrial fibrillation. Eur Heart J. 2005; 26 712-722 5 Bristow M R, Saxon L A, Boehmer J. et al . Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004; 350 2140-2150 6 Cazeau S, Leclercq C, Lavergne T. et al . Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001; 344 873-880 7 Cleland J G, Daubert J C, Erdmann E, Freemantle N, Gras D, Kappenberger L, Tavazzi L. Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005; 352 1539-1549 8 Daubert C, Gold M R, Abraham W T, Ghio S, Hassager C, Goode G, Szili-Török T, Linde C. REVERSE Study Group. Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial. J Am Coll Cardiol. 2009; 54 1837-1846 9 Dickstein K, Bogale N, Priori S, Auricchio A, Cleland J G, Gitt A, Limbourg T, Linde C, van Veldhuisen D J, Brugada J. Scientific Committee; National Coordinators. The European cardiac resynchronization therapy survey. Eur Heart J. 2009; 30 2450-2460 10 Dickstein K, Vardas P E, Auricchio A. et al . ESC Committee for Practice Guidelines. 2010 Focused Update of ESC Guidelines on device therapy in heart failure: an update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC Guidelines for cardiac and resynchronization therapy. Developed with the special contribution of the Heart Failure Association and the European Heart Rhythm Association. Europace. 2010; 12 1526-1536 11 Doshi R N, Daoud E G, Fellows C, Turk K, Duran A, Hamdan M H, Pires L A. PAVE Study Group. Left ventricular-based cardiac stimulation post AV nodal ablation evaluation (the PAVE study). J Cardiovasc Electrophysiol. 2005; 16 1160-1165 12 Farwell D, Patel N R, Hall A, Ralph S, Sulke A N. How many people with heart failure are appropriate for biventricular resynchronization?. Eur Heart J. 2000; 21 1246-1250 13 Hohnloser S H, Kuck K H, Dorian P, Roberts R S, Hampton J R, Hatala R, Fain E, Gent M, Connolly S J. DINAMIT Investigators. Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med. 2004; 351 2481-2488 14 Jung W, Andresen D, Block M, Boecker D, Hohnloser S H, Kuck, Sperzel J. Leitlinien zur Implantation von Defibrillatoren. Clin Res Cardiol. 2006; 95 696-708 15 Linde C, Abraham W T, Gold M R, St. John Sutton M, Ghio S, Daubert C. REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) Study Group. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms. J Am Coll Cardiol. 2008; 52 1834-1843 16 Moss A J, Hall W J, Cannom D S. et al . MADIT-CRT Trial Investigators. Cardiac-resynchronization therapy for the prevention of heart-failure events. N Engl J Med. 2009; 361 1329-1338 17 Moss A J, Zareba W, Hall W J. et al . Multicenter Automatic Defibrillator Implantation Trial II Investigators. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002; 346 877-883 18 Steinbeck G, Andresen D, Seidl K. et al, IRIS Investigators . Defibrillator implantation early after myocardial infarction. N Engl J Med. 2009; 361 1427-1436 19 Stellbrink C, Auricchio A, Diem B, Breithardt O A, Kloss M, Schöndube F A, Klein H, Messmer B J, Hanrath P. Potential benefit of biventricular pacing in patients with congestive heart failure and ventricular tachyarrhythmia. Am J Cardiol. 1999; 83 143D-150D 20 Stellbrink C, Breithardt O A, Franke A, Sack S, Bakker P, Auricchio A, Pochet T, Salo R, Kramer A, Spinelli J. PATH-CHF (PAcing THerapies in Congestive Heart Failure) Investigators; CPI Guidant Congestive Heart Failure Research Group. Impact of cardiac resynchronization therapy using hemodynamically optimized pacing on left ventricular remodeling in patients with congestive heart failure and ventricular conduction disturbances. J Am Coll Cardiol. 2001; 38 1957-1965 21 Tang A S, Wells G A, Talajic M. et al . Resynchronization-Defibrillation for Ambulatory Heart Failure Trial Investigators. Cardiac resynchronization therapy for mild-to-moderate heart failure. N Engl J Med. 2010; 363 2385-2395 22 Wilkoff B L, Cook J R, Epstein A E. et al . Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the dual chamber and VVI implantable defibrillator (DAVID) trial. J Am Med Assoc. 2002; 288 3115-3123 Prof. Dr. med. Christoph Stellbrink Klinik für Kardiologie und Internistische IntensivmedizinStädtische Kliniken Bielefeld Teutoburger Str. 50 33604 Bielefeld Telefon: 0521/5813401 Fax: 0521/5813498