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Psychiatr Prax 2012; 39(1): 7-13
DOI: 10.1055/s-0031-1276935
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Das Chamäleon der Psychiatrie – Psychiatrische Manifestationsformen der Neurosyphilis

The Chameleon of Psychiatry – Psychiatric Manifestations of NeurosyphilisFabian  Friedrich1 , Alexandra  Geusau2 , Michaela-Elena  Friedrich3 , Benjamin  Vyssoki3 , Tibor  Pfleger4 , Martin  Aigner1
  • 1Universitätsklinik für Psychiatrie und Psychotherapie, Abteilung für Sozialpsychiatrie, Medizinische Universität Wien, Österreich
  • 2Universitätsklinik für Dermatologie, Abteilung für Immundermatologie und Infektiöse Hautkrankheiten, Medizinische Universität Wien, Österreich
  • 3Universitätsklinik für Psychiatrie und Psychotherapie, Abteilung für Biologische Psychiatrie, Medizinische Universität Wien, Österreich
  • 4Abteilung für Innere Medizin, Elbe Klinikum Buxtehude, Deutschland
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Publication History

Publication Date:
28 November 2011 (online)

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Zusammenfassung

Anliegen Ziel dieser Arbeit ist eine Literaturübersicht über psychiatrische Manifestationsformen der Neurosyphilis. Methode Es wurde eine systematisierte elektronische Literatursuche nach publizierten Arbeiten ab dem Jahr 1995 durchgeführt. Ergebnisse Das klinische Erscheinungsbild der Neurosyphilis erstreckt sich über ein weites psychiatrisches Diagnosenspektrum nach ICD-10. Schlussfolgerungen Aufgrund des mannigfaltigen Erscheinungsbildes und des weltweiten Anstiegs der Syphilisinfektionen ist ein routinemäßiges Syphilis-Screening im psychiatrischen Bereich weiterhin indiziert und die Berücksichtigung der Neurosyphilis in der Differenzialdiagnostik aktueller denn je.

Abstract

Objective Recent epidemiological data have shown a significant increase in the prevalence of syphilis. If left untreated, up to 30 % of patients may develop tertiary syphilis, which can manifest as neurosyphilis. The aim of our review is to evaluate psychiatric manifestations of neurosyphilis according to ICD-10. Methods A systematic electronic search for published studies (1995–2010) was performed using the databases Medline, Embase, Cochrane as well as the search engines Scopus and Google Scholar. Results 113 studies were used for detailed analysis. Clinical manifestations of various forms of neurosyphilis are protean, numerous and non-specific and could be on the differential diagnosis for many psychiatric presentations according to ICD-10. Conclusion Due to our results, the difficulties in diagnosing syphilis and current epidemiological data, routine screening tests are still mandatory in the psychiatric field. Further, neurosyphilis still has to be considered in the differential diagnosis within the context of psychiatric conditions and diseases.

Schlüsselwörter

Neurosyphilis - Syphilis - Treponema pallidum - Screening

Keywords

neurosyphilis - syphilis - Treponema pallidum - screening

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Dr. Fabian Friedrich

Medizinische Universität Wien, Universitätsklinik für Psychiatrie und Psychotherapie

Währingergürtel 18–20

1090 Wien, Österreich

Email: fabian.friedrich@meduniwien.ac.at