Die Katarakt stellt die häufigste Ursache einer reversiblen Sehverschlechterung beim alternden Menschen dar. In Deutschland ist die altersbedingte Makuladegeneration (AMD) die häufigste Ursache einer gesetzlich anerkannten hochgradigen Sehbehinderung oder Erblindung. Es werden Fragen erörtert, die sich bei der Behandlung von Patienten mit gleichzeitigem Vorliegen von Katarakt und AMD stellen. Bei adäquater Indikationsstellung profitieren auch Patienten mit altersbedingter Makuladegeneration von einer Kataraktoperation. Der Visusanstieg durch die Operation ist bei der Mehrzahl der Patienten über Jahre nachweisbar. Nach derzeitigem Erkenntnisstand stellt die Kataraktoperation kein Risiko für die Progredienz einer AMD dar. Die Verschlechterung einer AMD nach Kataraktoperation ist ein zufälliges Ereignis, das durch die hohe Komorbidität von Katarakt und AMD bedingt ist. Es gibt kein belastbares Datenmaterial, das den Nutzen der Implantation von Blaufilter-Intraokularlinsen belegt.
Quellenangaben
1
Anonymous.
Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group.
Arch Ophthalmol.
1992;
110
1701-1708
2
Armbrecht A M, Findlay C, Aspinall P A et al.
Cataract surgery in patients with age-related macular degeneration: one-year outcomes.
J Cataract Refract Surg.
2003;
29
686-693
3
Armbrecht A M, Findlay C, Kaushal S et al.
Is cataract surgery justified in patients with age related macular degeneration? A visual function and quality of life assessment.
Br J Ophthalmol.
2000;
84
1343-1348
5
Baatz H, Darawsha R, Ackermann H et al.
Phacoemulsification does not induce neovascular age-related macular degeneration.
Invest Ophthalmol Vis Sci.
2008a;
49
1079-1083
6
Baatz H, Darawsha R, Scharioth G et al.
Visusverlauf nach Kataraktoperation bei Patienten mit altersassoziierter Makulopathie.
Ophthalmologe.
2008b;
105
927-930
9
Chew E Y, Sperduto R D, Milton R C et al.
Risk of advanced age-related macular degeneration after cataract surgery in the Age-Related Eye Disease Study: AREDS report 25.
Ophthalmology.
2009;
116
297-303
10
Cugati S, Mitchell P, Rochtchina E et al.
Cataract surgery and the 10-year incidence of age-related maculopathy: the Blue Mountains Eye Study.
Ophthalmology.
2006;
113
2020-2025
12
Dong L M, Stark W J, Jefferys J L et al.
Progression of age-related macular degeneration after cataract surgery.
Arch Ophthalmol.
2009;
127
1412-1419
13
Eberhard R, Roberti P, Prünte C.
Intraindividual comparison of color perception and contrast sensitivity with and without a blue light-filtering intraocular lens.
Eur J Ophthalmol.
2009;
19
235-239
14
Finger R P, Fimmers R, Holz F G et al.
Incidence of blindness and severe visual impairment in Germany: projections for 2030.
Invest Ophthalmol Vis Sci.
2011;
52
4381-4389
15
Forooghian F, Agrón E, Clemons T E et al.
Visual acuity outcomes after cataract surgery in patients with age-related macular degeneration: age-related eye disease study report no. 27.
Ophthalmology.
2009;
116
2093-2100
16
Graney M J, Applegate W B, Miller S T et al.
A clinical index for predicting visual acuity after cataract surgery.
Am J Ophthalmol.
1988;
105
460-465
19
Ho L, Boekhoorn S S, Liana et al.
Cataract surgery and the risk of aging macula disorder: the rotterdam study.
Invest Ophthalmol Vis Sci.
2008;
49
4795-4800
20
Hooper C Y, Lamoureux E L, Lim L et al.
Cataract surgery in high-risk age-related macular degeneration: a randomized controlled trial.
Clin Experiment Ophthalmol.
2009;
37
570-576
21
Kahn H A, Leibowitz H M, Ganley J P et al.
The Framingham Eye Study. II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study.
Am J Epidemiol.
1977;
106
33-41
22
Kaiserman I, Kaiserman N, Elhayany A et al.
Cataract surgery is associated with a higher rate of photodynamic therapy for age-related macular degeneration.
Ophthalmology.
2007;
114
278-282
23
Khalifa Y M, Pantanelli S M.
Quiescent posterior capsule trauma after intravitreal injection: implications for the cataract surgeon.
J Cataract Refract Surg.
2011;
37
1364
24
Klein R, Klein B E K, Tomany S C et al.
Association of emphysema, gout, and inflammatory markers with long-term incidence of age-related maculopathy.
Arch Ophthalmol.
2003a;
121
674-678
25
Klein R, Klein B E K, Tomany S C et al.
The association of cardiovascular disease with the long-term incidence of age-related maculopathy: the Beaver Dam Eye Study.
Ophthalmology.
2003b;
110
1273-1280
26
Klein R, Klein B E K, Wong T Y et al.
The association of cataract and cataract surgery with the long-term incidence of age-related maculopathy: the Beaver Dam eye study.
Arch Ophthalmol.
2002;
120
1551-1558
27
Lundström M, Brege K G, Florén I et al.
Cataract surgery and quality of life in patients with age related macular degeneration.
Br J Ophthalmol.
2002;
86
1330-1335
29
Mayer M J, Spiegler S J, Ward B et al.
Mid-frequency loss of foveal flicker sensitivity in early stages of age-related maculopathy.
Invest Ophthalmol Vis Sci.
1992;
33
3136-3142
32
Moss S E, Klein R, Klein B E et al.
Alcohol consumption and the 5-year incidence of age-related maculopathy: the Beaver Dam eye study.
Ophthalmology.
1998;
105
789-794
33
Pollack A, Marcovich A, Bukelman A et al.
Age-related macular degeneration after extracapsular cataract extraction with intraocular lens implantation.
Ophthalmology.
1996;
103
1546-1554
34
Rosenfeld P J, Shapiro H, Ehrlich J S et al.
Cataract Surgery in Ranibizumab-Treated Patients With Neovascular Age-Related Macular Degeneration From the Phase 3 ANCHOR and MARINA Trials.
Am J Ophthalmol.
2011;
152
793-798
35
Saeed M U, Prasad S.
Management of cataract caused by inadvertent capsule penetration during intravitreal injection of ranibizumab.
J Cataract Refract Surg.
2009;
35
1857-1859
37
Shuttleworth G N, Luhishi E A, Harrad R A.
Do patients with age related maculopathy and cataract benefit from cataract surgery?.
Br J Ophthalmol.
1998;
82
611-616
38
Sutter F K P, Menghini M, Barthelmes D et al.
Is pseudophakia a risk factor for neovascular age-related macular degeneration?.
Invest Ophthalmol Vis Sci.
2007;
48
1472-1475
40
van der Hoeve J.
Schädigungen des Auges durch Licht. Senile Linsentrübungen und senile Maculadegeneration.
Graefes Arch Clin Exp Ophthalmol.
1918;
98
49-66
41
Vingerling J R, Dielemans I, Bots M L et al.
Age-related macular degeneration is associated with atherosclerosis. The Rotterdam Study.
Am J Epidemiol.
1995;
142
404-409
42
Wang J J, Klein R, Smith W et al.
Cataract surgery and the 5-year incidence of late-stage age-related maculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies.
Ophthalmology.
2003;
110
1960-1967
44
Wirtitsch M G, Schmidinger G, Prskavec M et al.
Influence of blue-light-filtering intraocular lenses on color perception and contrast acuity.
Ophthalmology.
2009;
116
39-45
