3
Arbeitsgruppe Hochpräzisionsstrahlentherapie, OncoRay – Nationales Zentrum für Strahlenforschung in der Onkologie Dresden, Medizinische Fakultät, Universitätsklinikum Carl Gustav Carus, TU Dresden
2
Klinik für Nuklearmedizin, Medizinische Fakultät, Universitätsklinikum Carl Gustav Carus, TU Dresden
,
D. Zips
3
Arbeitsgruppe Hochpräzisionsstrahlentherapie, OncoRay – Nationales Zentrum für Strahlenforschung in der Onkologie Dresden, Medizinische Fakultät, Universitätsklinikum Carl Gustav Carus, TU Dresden
4
Arbeitsgruppe Experimentelle Strahlentherapie von Tumoren, OncoRay – Nationales Zentrum für Strahlenforschung in der Onkologie Dresden, Medizinische Fakultät, Universitätsklinikum Carl Gustav Carus, TU Dresden
Mit den aktuellen Entwicklungen der PET/CT-Bildgebung werden wichtige Anforderungen für den Einsatz der biologischen Bildgebung für die bildgestützte Hochpräzisionsstrahlentherapie wie Gewährleistung der bestmöglichen Koregistrierung, hohe Genauigkeit der quantitativen funktionellen PET-Parameter adressiert. Diese technischen Entwicklungen umfassen die Time-of-Flight (TOF) Technik, Verbesserung der tomografischen Bildrekonstruktion, Weiterentwicklung von Methoden zur Berücksichtigung von atmungskorrelierter Bewegung und die Datenverarbeitung. Damit werden die technischen Voraussetzungen zur Testung von neuen Konzepten der biologisch individualisierten Hochpräzisionsstrahlentherapie mit dem Ziel der effektiveren Behandlung von Krebserkrankungen weiter verbessert.
Abstract
Current developments in PET/CT imaging address important requirements for the implementation of biological imaging for image-guided high-precision radiotherapy, i. e. high accuracy in co-registration and quantitative assessment of PET parameters. These developments include the time-of-flight technique, improved tomographic image reconstruction, further development of breathing-related movement and data processing. This provides an improved technical basis for the testing of novel concepts in biologically individualized high-precision radiotherapy aiming for better treatment of cancer patients.
Unterstützt durch das BMBF (03ZIK/OncoRay und 03NUK006B).
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