DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2011; 136(33): 1678-1683DOI: 10.1055/s-0031-1281577 Prinzip & Perspektive | Review article Immunologie © Georg Thieme Verlag KG Stuttgart · New York Das adaptive Immunsystem Adaptive immunity T. Kamradt1 , K. Ferrari-Kühne1 , 2 1Institut für Immunologie, Universitätsklinikum Jena 2Klinik für Herz-Thoraxchirurgie, Universitätsklinikum Jena Recommend Article Abstract Buy Article Schlüsselwörter T-Lymphozyten - B-Lymphozyten - T-Helferzellen - regulatorische T-Zellen - Antikörper - Immundefekte Keywords T-lymphocytes - B-lymphocytes - T-helper cells - regulatory T-cells - antibodies - immunodeficiency Full Text References Literatur 1 Bousfiha A, Picard C, Boisson-Dupuis S. et al . Primary immunodeficiencies of protective immunity to primary infections. Clin Immunol. 2010; 135 204-209 2 Germain R N. Special regulatory T-cell review: A rose by any other name: from suppressor T cells to Tregs, approbation to unbridled enthusiasm. Immunology. 2008; 123 20-27 3 Hiepe F, Dorner T, Hauser A E. et al . Long-lived autoreactive plasma cells drive persistent autoimmune inflammation. Nat Rev Rheumatol. 2011; 7 170-178 4 Kamradt T, Mitchison N A. Tolerance and autoimmunity. N Engl J Med. 2001; 344 655-664 5 Marodi L, Casanova J L. Primary immunodeficiencies may reveal potential infectious diseases associated with immune-targeting mAb treatments. J Allergy Clin Immunol. 2010; 126 910-917 6 Nimmerjahn F, Ravetch J V. Antibody-mediated modulation of immune responses. Immunol Rev. 2010; 236 265-275 7 Rahman A, Isenberg D A. Systemic lupus erythematosus. N Engl J Med. 2008; 358 929-939 8 Siffrin V, Brandt A U, Herz J. et al . New insights into adaptive immunity in chronic neuroinflammation. Advances in immunology. 2007; 96 1-40 9 von Boehmer H, Melchers F. Checkpoints in lymphocyte development and autoimmune disease. Nat Immunol. 2010; 11 14-20 10 Warnatz K, Peter H H. [Classification and diagnosis of immunodeficiency syndromes]. Internist (Berl). 2004; 45 868-881 Prof. Dr. med. Thomas Kamradt Institut für ImmunologieUniversitätsklinikum Jena 07740 Jena Phone: 03641/938780 Email: thomas.kamradt{at} med.uni-jena.de