Neuropediatrics 2011; 42(03): 90-96
DOI: 10.1055/s-0031-1283157
Review Article
Georg Thieme Verlag Stuttgart · New york

Toward Multi-Scale Computational Modeling in Developmental Disability Research

O. Dammann
1   Floating Hospital for Children at Tufts Medical Center, Division of Newborn Medicine, Boston, Massachusetts, USA
2   Hannover Medical School, Department of Gynecology and Obstetrics, Perinatal Neuroepidemiology Unit, Hannover, Germany
,
P. Follett
3   Lewis Rhodes Labs, Inc., Acton, Massachusetts, USA
› Institutsangaben
Weitere Informationen

Publikationsverlauf

received 17. Februar 2011

accepted 22. Mai 2011

Publikationsdatum:
19. Juli 2011 (online)

Preview

Abstract

The field of theoretical neuroscience is gaining increasing recognition. Virtually all areas of neuroscience offer potential linkage points for computational work. In developmental neuroscience, main areas of research are neural development and connectivity, and connectionist modeling of cognitive development. In this paper, we suggest that computational models can be helpful tools for understanding the pathogenesis and consequences of perinatal brain damage and subsequent developmental disability. In particular, designing multi-scale computational models should be considered by developmental neuroscientists interested in helping reduce the risk for developmental disabilities.