Die vorliegende Übersichtsarbeit sondiert auf Basis internationaler Reviews der vergangenen Dekade Dosis-Wirkungs-Beziehungen körperlicher Aktivität zur Prävention und Therapie von Zivilisationskrankheiten. Empirisch gesicherte Hinweise auf Dosis-Wirkungs-Beziehungen finden sich für 8 der 10 am besten untersuchten chronischen Erkrankungen. Für 6 (Prävention) bzw. 4 Krankheitsbilder (Therapie) lassen sich Empfehlungen zur minimalen wirksamen Dosis (1–7 h moderate bis intensive körperliche Aktivität pro Woche) ableiten. Steigerungen der Bewegungsdosis gehen mit größeren gesundheitswirksamen Effekten einher.
Based on published international reviews, this narrative review analyzes the dose-response relation between physical activity and preventive as well as therapeutic effects on chronic diseases. There is at least satisfactory evidence for dose-response in 8 out of 10 of the most frequently studied chronic diseases. For 6 (prevention) and 4 chronic diseases (therapy), respectively, there seems to be a minimum effective dose between 1 and 7 hours of moderate to vigorous physical activity per week. Increasing the dose of physical activity leads to better effects on health.
Stichworte:
Bewegung - Prävention - Therapie - chronische Erkrankung - Dosis-Wirkungs-Beziehung
Key words:
exercise - prevention - therapy - chronic disease - dose-response
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Korrespondenzadresse
Dr. C. Thiel
Goethe-Universität · Institut für Sportwissenschaften / Abteilung Sportmedizin
Ginnheimer Landstr. 39
60487 Frankfurt / Main
Telefon: 0 69 / 79 82 45 / 06
eMail: c.thiel@sport.uni-frankfurt.de