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Zeitschrift für Phytotherapie 2012; 33(1): 14-18
DOI: 10.1055/s-0031-1286041
Forschung
Influenza
© Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Der Pflanzenextrakt Cystus052 blockiert Grippeviren

Stephan Ludwig

Subject Editor:
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Publication History

Publication Date:
22 March 2012 (online)

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Zusammenfassung

Infektionen mit Influenza-A-Viren (»Virusgrippe«) sind nach wie vor eine große gesundheitliche Bedrohung für die Menschheit. Die letzte, relativ mild verlaufene Influenza-Pandemie im Jahr 2009 hat deutlich gezeigt, dass Impfstoffe für die Frühphase einer Pandemie keine Option darstellen. Auch die derzeit zugelassenen antiviralen Medikamente sind kritisch zu sehen, da eine ständige Zunahme von resistenten Influenza-Virusvarianten zu beobachten ist. Dies zeigt, dass wir dringend neue antivirale Agenzien gegen die Influenza benötigen. Pflanzenprodukte aus der traditionellen Medizin können hier eine sichere und wirksame Alternative sowohl für die Therapie als auch für die Prophylaxe sein. Dieser Übersichtsartikel stellt den Pflanzenextrakt Cystus052 aus der graubehaarten Zistrose in den Mittelpunkt, für den nicht nur eine Wirkung gegen Grippeviren gezeigt wurde, sondern der auch über einen neuartigen antiviralen Mechanismus wirkt: Die Viren werden durch eine nichtpharmakologische Wechselwirkung mit den Extraktbestandteilen am Eindringen in die Wirtszelle gehindert.

Summary

The plant extract Cystus052 blocks influenza viruses

Infections with Influenza A viruses are still a serious burden for mankind. Although the recent influenza pandemic in 2009 took a rather mild course, the relatively long time period since a vaccine was available highlighted the fact, that vaccination is not an option for the early phase of a pandemic outbreak. In addition, the increasing incidence of resistance to the currently licensed influenza drugs indicates the urgent need for novel antiviral agents against influenza. Antiviral acting plant products from traditional medicine could be a promising alternative for prevention and therapy of influenza. This article highlights findings regarding the plant extract Cystus052 from the Mediterranean plant pink rockrose. This extract has been shown to be an efficient antiviral against influenza viruses in cell culture and animals. It acts via a novel mechanism, namely non-pharmacological interaction with the virus particle to prevent entry into host cells.

Key words

Influenza - virus - Cistus incanus L. - mode of action

Schlüsselwörter

Influenza - Virus - Cistus incanus L. - Wirkmechanismus
 

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