Abstract
This brief review article describes the progress made in the
synthesis of 1,2,3-triazole-fused heterocycles, over the last ten years,
mainly by azide-alkyne cycloaddition reactions. In this
article, the emphasis is on the various aspects of 1,3-dipolar cycloaddition
reactions, especially intramolecular azide-alkyne dipolar cycloaddition
reactions.
1 Introduction
2 Synthesis of Fused Triazoles
2.1 Synthesis of 1,2,3-Triazole-Fused Heterocycles by Huisgen (Thermal)
1,3-Cycloaddition Reactions
2.2 Microwave-Assisted 1,3-Dipolar Cycloaddition Reactions for
the Synthesis of Condensed Triazoles
2.3 Copper-Catalyzed Cycloaddition Reactions for the Synthesis
of Condensed Triazoles
2.4 Copper/Other-Metal-Catalyzed Cycloaddition Reactions for
the Synthesis of Condensed Triazoles
2.5 Synthesis of Triazole-Containing Macrocycles by Azide-Alkyne
1,3-Dipolar Cycloaddition Reactions
3 Conclusion
Key words
1,2,3-triazole - azide - alkyne - cycloaddition - heterocycles
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