Abstract
An efficient synthetic protocol for 2-(1-aryl-2-nitroethyl)-3-arylaminoacrylates
was successfully developed by the one-pot domino reaction of arylamines,
methyl propiolate, and nitrostyrenes. The reaction involves the
formation of β-enamino ester and its sequential Michael
addition to nitrostyrene.
Key words
domino reaction - β-enamino ester - electron-deficient alkyne - nitrostyrene - acrylate
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