Knorpelregeneration

M. O. Brix; C. Chiari

doi:10.1055/s-0032-1315242

Zeitschrift für Orthopädie und Unfallchirurgie, Table of Contents

Z Orthop Unfall 2012; 150(4): e121-e142
DOI: 10.1055/s-0032-1315242

Refresher Orthopädie und Unfallchirurgie

Georg Thieme Verlag KG Stuttgart · New York

Knorpelregeneration

M. O. Brix

¹Universitätsklinik für Orthopädie, Medizinsche Universität Wien, Wien

,

C. Chiari

¹Universitätsklinik für Orthopädie, Medizinsche Universität Wien, Wien

› Author Affiliations

Abstract

Zusammenfassung

Die Behandlung von Schäden des Gelenkknorpels stellt große Anforderungen an die Medizin. Für den Patienten bedeutet ein Knorpelschaden Schmerzen, Funktionseinschränkung und eine verminderte Lebensqualität, aber auch ein erhöhtes Risiko für einen frühzeitigen Gelenkersatz. Heute gibt es eine Vielzahl an Therapiemöglichkeiten, die eine Verbesserung der Situation für den Patienten erlauben. Mosaikplastik, knochenmarkstimulierende und zellbasierte Verfahren stehen seit Jahren in klinischer Anwendung. In diesem Artikel werden die Klassifikation und Abklärung von Knorpelschäden sowie verschiedene Knorpelreparaturverfahren und deren Indikationen dargestellt.

Abstract

Articular cartilage damage is challenging to treat. The patient has to deal with pain, functional impairment and compromized quality of life. Ultimately, he has to face the risk of early total joint replacement. A variety of treatment options is available to improve the situation for the patient. Mosaicplasty, bone marrow-stimulating techniques and cell-based methods have been in clinical use for years. This article explains preoperative diagnosis and classification systems of cartilage lesions and presents different cartilage repair procedures and their indications.

Key words

Knorpel - Knorpelregeneration - Knie - Knorpelzelltransplantation - Mikrofrakturierung

Key words

cartilage - cartilage repair - knee - chondrocyte transplantation - microfracturing

Full Text

References

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