A Convenient Conversion of Substituted Cyclohexenones into Aryl Methyl Ketones

Abstract

This work describes a straightforward multistep conversion of substrates containing a cyclohexenone moiety into mono-, bi- and tricyclic aryl methyl ketones in one single working process. Crucial steps are the addition of 1-ethoxyvinyllithium to the carbonyl group, followed by acid-catalyzed enol ether hydrolysis, dehydration, and dehydrogenation.

Key words

ketones - acetyl anion equivalents - vinyl ether - carbazole - aromatization

• References

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