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DOI: 10.1055/s-0032-1326211
Abdominelles Kompartmentsyndrom
Publication History
Publication Date:
15 May 2013 (online)
Pathophysiologie
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Der normale intraabdominelle Druck beträgt etwa 5 mmHg.
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Liegt der intraabdominelle Druck konstant über 12 mmHg, spricht man von einer intraabdominellen Hypertonie.
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Liegt der intraabdominelle Druck über 20 mmHg und besteht gleichzeitig eine Organdysfunktion, spricht man von einem abdominellen Kompartmentsyndrom.
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Teufelskreis: Ein steigender intraabdomineller Druck führt zur Kompression der intraabdominellen und retroperitonealen Gefäße, was zur venösen Stase mit anschließender Flüssigkeitssequestration und Beeinträchtigung der arteriellen Perfusion führt.
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Die intraabdominelle Hypertonie ist ein auf der Intensivstation häufiges, aber auch oft übersehenes Krankheitsbild, das ohne Prodomi auftreten kann.
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Die Letalität des abdominellen Kompartmentsyndroms kann bis zu 60 % betragen.
Diagnostik
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Erste manifeste Organdysfunktion ist eine Einschränkung der Nierenfunktion.
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Standard ist die indirekte Messung des Blasendrucks über einen Katheter. Ein alternatives Messverfahren ist die Messung des Mageninnendrucks.
Therapie
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Eine frühzeitige Diagnose und adäquate therapeutische Intervention senken die Morbidität und Mortalität. Die Ziele der Interventionen sind eine Senkung des intraabdominellen Drucks und ein abdomineller Perfusionsdruck von 50 – 60 mmHg.
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Konservative Maßnahmen: u. a. Muskelrelaxation, Prokinetika und rektale Dekompression, Anhebung des kolloidosmotischen Drucks in Kombination mit Diuretika oder Nierenersatzverfahren, Drainagen.
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Operative Maßnahmen: dekompressive Laparotomie und Anlage eines Laparostomas, temporärer Bauchdeckenverschluss mit OPSITE-Folie, synthetischem Netz oder Unterdrucktherapie.
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