Ernährungsmarker – Warum sollten wir Präalbumin bei Dialysepatienten messen?

Roman Fiedler

doi:10.1055/s-0032-1329385

Dialyse aktuell, Table of Contents

Dialyse aktuell 2012; 16(7): 404-407
DOI: 10.1055/s-0032-1329385

Dialyse

Ernährungsmarker – Warum sollten wir Präalbumin bei Dialysepatienten messen?

Nutrition markers – Why should we measure prealbumin in dialysis patients?

Roman Fiedler

¹Klinik für Innere Medizin II, Universitätsklinikum der Martin-Luther-Universität Halle-Wittenberg, Halle (Saale) (Klinikdirektor: Prof. Dr. habil. Matthias Girndt)

› Author Affiliations

Abstract

Präalbumin (Transthyretin) ist ein valider und hilfreicher Parameter für die Evaluation einer Protein-Energie-Mangelernährung (PEM) in der klinischen Praxis, insbesondere auch bei Dialysepatienten. Im Folgenden wird auf die diagnostische und prädiktive Bedeutung erniedrigter Präalbumin-Serum-Spiegel (< 30 mg/dl) sowie auf einen möglichen ernährungstherapierelevan-ten Präalbuminanstieg (> 3 mg/dl über 3 Monate) eingegangen. Präalbumin sollte daher als gängiger Laborroutineparameter bei Dialysepatienten gesehen und dementsprechend auch gemessen werden.

Prealbumin (transthyretin) is a valid and useful parameter for the evaluation of protein-energy malnutrition (PEM) in clinical practice, especially in dialysis patients. The diagnostic and predictive importance of decreased prealbumin serum levels (< 30 mg/dl) will be explained as well as possible relevant elevation of prealbumin concentration (> 3 mg/dl over 3 months) by nutritional supplements. Prealbumin should be seen as a routine laboratory parameter in dialysis patients and therefore also measured.

Key words

mortality - nutritional status - prealbumin - protein-energy malnutrition

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References

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