Synthesis 2014; 46(18): 2430-2435
DOI: 10.1055/s-0033-1340193
paper
© Georg Thieme Verlag Stuttgart · New York

Fluorescent-Labeled Amino Acid–Antibiotic Conjugates

Anand D. Tiwari
a   Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
,
Siva S. Panda*
a   Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
,
Abdullah M. Asiri
b   Chemistry Department, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
c   Center for Advanced Materials Research (CEAMR), King Abdulaziz University, Jeddah 21589, Saudi Arabia   Fax: +1(352)3929199   Email: sspanda12@gmail.com   Email: charlesdennishall@gmail.com
,
C. Dennis Hall*
a   Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
,
Alan R. Katritzky †
a   Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
b   Chemistry Department, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
› Author Affiliations
Further Information

Publication History

Received: 31 March 2014

Accepted after revision: 01 May 2014

Publication Date:
24 June 2014 (online)


Abstract

Benzotriazole-mediated synthesis provides novel fluorescent-labeled amino acid–quinolone antibiotic conjugates in good yields with retention of chirality. The photophysical properties of all the fluorescent-labeled antibiotic conjugates were determined.

Supporting Information