Synthesis of Cyclopropanated 7-Oxabenzonorbornadienes

Abstract

Symmetrical and unsymmetrical 7-oxabenzonorbornadienes have been cyclopropanated using diazomethane gas under palladium catalysis. Good to excellent isolated yields (64–96%) of cyclopropanated oxabenzonorbornadienes were obtained, and excellent stereoselectivities were observed with exo-cyclopropanes as the only stereoisomeric products.

Key words

7-oxabenzonorbornadienes - cyclopropanation - diazo compounds - diastereoselectivity - palladium catalysis

• References

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