TumorDiagnostik & Therapie, Inhaltsverzeichnis TumorDiagnostik & Therapie 2014; 35(5): 264-266DOI: 10.1055/s-0034-1369211 Schwerpunkt: Gastrointestinale Stromatumoren Georg Thieme Verlag KG Stuttgart · New York Übersicht – Molekulare Diagnostik bei gastrointestinalen Stromatumoren S. Huss , I. Grünewald , M. Trautmann , J. Sperveslage , W. Hartmann , E. Wardelmann Artikel empfehlen Abstract Artikel einzeln kaufen Volltext Referenzen Literatur 1 Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-580 2 Heinrich MC, Corless CL, Duensing A et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003; 299: 708-710 3 Wardelmann E, Hohenberger P, Reichardt P et al. Gastrointestinal stromal tumors of the stomach. Updates and differences compared to other locations. Pathologe 2010; 31: 195-198 4 Huss S, Künstlinger H, Wardelmann E et al. A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del). Mod Pathol 2013; 26: 1004-1012 5 Künstlinger H, Huss S, Merkelbach-Bruse S et al. Gastrointestinal stromal tumors with KIT exon 9 mutations: Update on genotype-phenotype correlation and validation of a high-resolution melting assay for mutational testing. Am J Surg Pathol 2013; 37: 1648-1659 6 Agaimy A, Vassos N, Croner RS. Gastrointestinal manifestations of neurofibromatosis type 1 (Recklinghausen‘s disease): clinicopathological spectrum with pathogenetic considerations. Int J Clin Exp Pathol 2012; 5: 852-862 7 Carney J, Stratakis C. Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad. Am J Med Gen 2002; 108: 132-139 8 Postow MA, Robson ME. Inherited gastrointestinal stromal tumor syndromes: mutations, clinical features and therapeutic implications. Clin Sarc Res 2012; 2: 16 9 Hostein I, Faur N, Primois C et al. BRAF mutation status in gastrointestinal stromal tumors. Am J Clin Pathol 2010; 133: 141-148 10 Zhang L, Smyrk T, Young WJ et al. Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. Am J Surg Pathol 2010; 34: 53-64 11 Killian JK, Kim SY, Miettinen M et al. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discov 2013; 3: 648-657 12 Miettinen M, Lasota J. Gastrointestinal stromal tumors: Pathology and prognosis at different sites. Semin Diagn Pathol 2006; 23: 70-83 13 Serrano C, George S. Recent advances in the treatment of gastrointestinal stromal tumors. Ther Adv Med Oncol 2014; 6: 115-127
