Dtsch Med Wochenschr 2014; 139(23): 1237-1239
DOI: 10.1055/s-0034-1370032
Verdauungs- und Stoffwechselkrankheiten | Commentary
Gastroenterologie, Infektiologie
© Georg Thieme Verlag KG Stuttgart · New York

Übertragung von Darmflora („Stuhltransplantation“): wann und für wen?

Fecal microbiota transplantation: When and for whom?
R. Schmelz
1   Medizinische Klinik und Poliklinik 1, Universitätsklinikum Carl Gustav Carus der TU Dresden
,
J. Hampe
1   Medizinische Klinik und Poliklinik 1, Universitätsklinikum Carl Gustav Carus der TU Dresden
› Author Affiliations
Further Information

Publication History

Publication Date:
27 May 2014 (online)

    Permissions and Reprints

Schlüsselwörter

Stuhltransplantation - Clostridum difficile

Keywords

fecal microbiota transplantation - Clostridium difficile
 

  • Literatur

  • 1 Anderson JL, Edney RJ, Whelan K. Faecal microbiota transplantation in the management of inflammatory bowel disease. Aliment Pharmacol Ther 2012; 36: 503-516
    CrossrefPubMedGoogle Scholar
  • 2 Arumugam M, Raes J, Pelletier E et al. Enterotypes of the human gut microbiome. Nature 2011; 473: 174-180. Erratum: p. 666
    CrossrefGoogle Scholar
  • 3 Eiseman B, Silen W, Bascom GS et al. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 1958; 44: 854-859
    Google Scholar
  • 4 Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis 2011; 53: 994-1002
    CrossrefGoogle Scholar
  • 5 Kassam Z, Lee CH, Yuan Y et al. Fecal microbiota transplantation for Clostridium difficile infection. Am J Gastroenterol 2013; 108: 500-508
    CrossrefPubMedGoogle Scholar
  • 6 Kump PK, Gröchenig HP, Lackner S et al. Alteration of intestinal dysbiosis by fecal microbiota transplantation does not induce remission in patients with chronic active ulcerative colitis. Inflamm Bowel Dis 2013; 19: 2155-2165
    CrossrefGoogle Scholar
  • 7 Ley RE, Turnbaugh PJ, Klein S et al. Microbial ecology: human gutmicrobes associated with obesity. Nature 2006; 444: 1022-1023
    CrossrefGoogle Scholar
  • 8 van Nood E, Vrieze A, Nieuwdorp M et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013; 368: 407-415
    CrossrefPubMedGoogle Scholar
  • 9 Qin J, Li R, Raes J et al. MetaHIT Consortium: A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464: 59-65
    CrossrefGoogle Scholar
  • 10 Ridaura VK, Faith JJ, Rey FE et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341: 1241214
    CrossrefGoogle Scholar
  • 11 Smits LP, Bouter KE, de Vos WM et al. Therapeutic potential of fecal microbiota transplantation. Gastroenterology 2013; 145: 946-953
    CrossrefGoogle Scholar
  • 12 Stepan C, Surawicz CM. Treatment strategies for C. difficile associated diarrhea. Acta Gastroenterol Latinoam 2007; 37: 183-191
    Google Scholar
  • 13 Surawicz CM, Alexander J. Treatment of refractory and recurrent Clostridium difficile infection. Nat Rev Gastroenterol Hepatol 2011; 8: 330-339
    CrossrefGoogle Scholar
  • 14 Vardakas KZ, Polyzos KA, Patouni K et al. Treatment failure and recurrence of Clostridium difficile infection following treatment with vancomycin or metronidazole. Int J Antimicrob Agents 2012; 40: 1-8
    CrossrefGoogle Scholar
  • 15 Vrieze A, Van Nood E, Holleman F et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology 2012; 143: 913-916
    CrossrefGoogle Scholar
  • 16 Zhang F, Luo W, Shi Y et al. Should we standardize the 1,700-year-old fecal microbiota transplantation?. Am J Gastroenterol 2012; 107: 1755; author reply p. 1755-1776
    Google Scholar