Strategies for the Synthesis of Antifeedant Leucosceptroid Natural Products

Abstract

The evolving pathogen resistance in agricultural pests requires the development of novel chemical agents to maintain efficient pest control. Biological screening of natural products isolated from Leucosceptrum canum Smith led to the discovery of active antifeedant sesterterpenoids. This article highlights recent progress towards the synthesis of these natural products.

1 Introduction

2 Synthesis of the Leucosceptroid Core Structure

3 Total Synthesis of Leucosceptroid B

4 Towards the Collective Synthesis of Leucosceptroid Natural Products

5 Total Synthesis of Leucosceptroids A and B

6 Summary

Key words

leucosceptroids - natural products - total synthesis - terpenoids - sesterterpenoids

• References and Notes

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