Palladium-Catalyzed Allylic Amination of Homoallylic Alcohols with Amines via Carbon–Carbon Bond Cleavage

Abstract

An efficient approach for palladium(II) acetate catalyzed allylic amination of homoallylic alcohols with various amines via sequential retro-allylation and amination was developed, which afforded the corresponding allylic amines in up to 98% yield.

Key words

C–C bond activation - allylic amination - homoallylic alcohols - palladium - allylic amines

• References


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