Easy Synthesis of trans-4,5-Dihydroxy-2-imidazolidinone and 2,4-Dimethylglycoluril

Abstract

A simple and efficient synthesis of 2,4-dimethylglycoluril involving the formation of trans-4,5-dihydroxy-2-imidazolidinone is presented as well as a reproducible protocol to reduce contamination with its decomposition products, identified as urea and 1,3-dimethylimidazolidine-2,4-dione.

Key words

glyoxal - urea - 1,3-dimethylurea - trans-4,5-dihydroxy-2-imidazolidinone - 2,4-dimethylglycoluril

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